{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:53:21Z","timestamp":1787237601820,"version":"3.56.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"14","funder":[{"name":"Genomic Science Program"},{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006206","name":"Biological and Environmental Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006206","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Plant Microbe Interfaces Scientific Focus Area"},{"DOI":"10.13039\/100007000","name":"Laboratory Directed Research and Development Program","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007000","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100006228","name":"Oak Ridge National Laboratory","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016818","name":"UT-Battelle, LLC","doi-asserted-by":"publisher","award":["DE-AC05-00OR22725"],"award-info":[{"award-number":["DE-AC05-00OR22725"]}],"id":[{"id":"10.13039\/100016818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Antimicrobial peptides (AMPs) are promising alternative antimicrobial agents. Currently, however, portable, user-friendly and efficient methods for predicting AMP sequences from genome-scale data are not readily available. Here we present amPEPpy, an open-source, multi-threaded command-line application for predicting AMP sequences using a random forest classifier.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and implementation<\/jats:title>\n                    <jats:p>amPEPpy is implemented in Python 3 and is freely available through GitHub (https:\/\/github.com\/tlawrence3\/amPEPpy).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Supplementary information<\/jats:title>\n                    <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btaa917","type":"journal-article","created":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T07:11:25Z","timestamp":1602918685000},"page":"2058-2060","source":"Crossref","is-referenced-by-count":122,"title":["amPEPpy 1.0: a portable and accurate antimicrobial peptide prediction tool"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7380-489X","authenticated-orcid":false,"given":"Travis J","family":"Lawrence","sequence":"first","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana L","family":"Carper","sequence":"additional","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret K","family":"Spangler","sequence":"additional","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa A","family":"Carrell","sequence":"additional","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3207-1466","authenticated-orcid":false,"given":"Tom\u00e1s A","family":"Rush","sequence":"additional","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J","family":"Minter","sequence":"additional","affiliation":[{"name":"Cryomagnetics, Inc. , Oak Ridge, TN 37830, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Weston","sequence":"additional","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessy L","family":"Labb\u00e9","sequence":"additional","affiliation":[{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,2]]},"reference":[{"key":"2023061310292465200_btaa917-B1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41598-018-19752-w","article-title":"AmPEP: sequence-based prediction of antimicrobial peptides using distribution patterns of amino acid properties and random forest","volume":"8","author":"Bhadra","year":"2018","journal-title":"Sci. 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