{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:16:28Z","timestamp":1760710588651,"version":"3.37.3"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"20","license":[{"start":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T00:00:00Z","timestamp":1621814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"ARC Future Fellowship","award":["FT170100359"],"award-info":[{"award-number":["FT170100359"]}]},{"name":"UNSW Scientia fellowship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Motivation<\/jats:title>\n                  <jats:p>CircRNAs are covalently closed RNA molecules that are particularly abundant in the brain. While circRNA expression data from the human brain is rapidly accumulating, integration of large-scale datasets remains challenging and time-consuming, and consequently an integrative view of circRNA expression in the human brain is currently lacking.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>NeuroCirc is a web-based resource that allows interactive exploration of multiple types of circRNA data from the human brain, including large-scale expression datasets, circQTL data and circRNA expression across neuronal differentiation and cellular maturation time-courses. NeuroCirc also allows users to upload their own circRNA expression data and explore it in the integrative platform, thereby supporting circRNA prioritization for experimental validation and functional studies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>NeuroCirc is freely available at: https:\/\/voineagulab.github.io\/NeuroCirc\/. The source code and user documentation are available at: https:\/\/github.com\/Voineagulab\/NeuroCirc.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btab230","type":"journal-article","created":{"date-parts":[[2021,5,23]],"date-time":"2021-05-23T11:07:10Z","timestamp":1621768030000},"page":"3664-3666","source":"Crossref","is-referenced-by-count":4,"title":["NeuroCirc: an integrative resource of circular RNA expression in the human brain"],"prefix":"10.1093","volume":"37","author":[{"given":"Kieran","family":"Walsh","sequence":"first","affiliation":[{"name":"Department of Biotechnology and Biomolecular Sciences, University of New South Wales , Sydney, NSW 2052, Australia"}]},{"given":"Akira","family":"Gokool","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biomolecular Sciences, University of New South Wales , Sydney, NSW 2052, Australia"}]},{"given":"Hamid","family":"Alinejad-Rokny","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Systems Biology and Health Data Analytics Lab, The Graduate School of Biomedical Engineering, University of New South Wales , Sydney, NSW 2052, Australia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4162-3872","authenticated-orcid":false,"given":"Irina","family":"Voineagu","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biomolecular Sciences, University of New South Wales , Sydney, NSW 2052, Australia"}]}],"member":"286","published-online":{"date-parts":[[2021,5,24]]},"reference":[{"key":"2023051608574737600_btab230-B1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrm.2015.32","article-title":"The biogenesis and emerging roles of circular RNAs","volume":"17","author":"Chen","year":"2016","journal-title":"Nat. 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