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It builds on the SummarizedExperiment data structure to create a centralized pipeline framework for storing data, analysis steps, results and visualizations. maplet\u2019s key design feature is its modularity, which offers several advantages, such as ensuring code quality through the maintenance of individual functions and promoting collaborative development by removing technical barriers to code contribution. With over 90 functions, the package includes a wide range of functionalities, covering many widely used statistical approaches and data visualization techniques.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>The maplet package is implemented in R and freely available at https:\/\/github.com\/krumsieklab\/maplet<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btab741","type":"journal-article","created":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T03:37:46Z","timestamp":1634960266000},"page":"1168-1170","source":"Crossref","is-referenced-by-count":31,"title":["<tt>maplet<\/tt>: an extensible R toolbox for modular and reproducible metabolomics pipelines"],"prefix":"10.1093","volume":"38","author":[{"given":"Kelsey","family":"Chetnik","sequence":"first","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"given":"Elisa","family":"Benedetti","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"given":"Daniel P","family":"Gomari","sequence":"additional","affiliation":[{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Neuherberg, Germany"}]},{"given":"Annalise","family":"Schweickart","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"given":"Richa","family":"Batra","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"given":"Mustafa","family":"Buyukozkan","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"given":"Zeyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4666-0923","authenticated-orcid":false,"given":"Matthias","family":"Arnold","sequence":"additional","affiliation":[{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Neuherberg, Germany"}]},{"given":"Jonas","family":"Zierer","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9638-3912","authenticated-orcid":false,"given":"Karsten","family":"Suhre","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Weill Cornell Medical College\u2014Qatar Education City , Doha, Qatar"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4734-3791","authenticated-orcid":false,"given":"Jan","family":"Krumsiek","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, Institute for Computational Biomedicine, Englander Institute for Precision Medicine, Weill Cornell Medicine , New York, NY 10021, USA"}]}],"member":"286","published-online":{"date-parts":[[2021,10,25]]},"reference":[{"key":"2023020108524057100_btab741-B1","article-title":"magrittr: a forward-pipe operator for R","author":"Bache","year":"2020"},{"key":"2023020108524057100_btab741-B2","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/533452a","article-title":"1,500 scientists lift the lid on reproducibility","volume":"533","author":"Baker","year":"2016","journal-title":"Nat. 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