{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T04:34:16Z","timestamp":1774499656281,"version":"3.50.1"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Union\u2019s Horizon 2020","award":["681605"],"award-info":[{"award-number":["681605"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>Visualization and inference of population structure is increasingly important for fundamental and applied research. Here, we present Struct-f4, providing automated solutions to characterize and summarize the genetic ancestry profile of individuals, assess their genetic affinities, identify admixture sources and quantify admixture levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>Struct-f4 is written in Rcpp and relies on f4-statistics and Markov Chain Monte Carlo (MCMC) optimization. It is freely available under GNU General Public License in Bitbucket (https:\/\/bitbucket.org\/plibradosanz\/structf4\/).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btac046","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T20:13:32Z","timestamp":1643055212000},"page":"2070-2071","source":"Crossref","is-referenced-by-count":25,"title":["Struct-f4: a Rcpp package for ancestry profile and population structure inference from <i>f<\/i>4-statistics"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5974-2189","authenticated-orcid":false,"given":"Pablo","family":"Librado","sequence":"first","affiliation":[{"name":"Centre for Anthropobiology and Genomics of Toulouse, CNRS UMR 5288, Universit\u00e9 de Toulouse, Universit\u00e9 Paul Sabatier, 31000 Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludovic","family":"Orlando","sequence":"additional","affiliation":[{"name":"Centre for Anthropobiology and Genomics of Toulouse, CNRS UMR 5288, Universit\u00e9 de Toulouse, Universit\u00e9 Paul Sabatier, 31000 Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"key":"2023020109013827400_btac046-B1","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1101\/gr.094052.109","article-title":"Fast model-based estimation of ancestry in unrelated individuals","volume":"19","author":"Alexander","year":"2009","journal-title":"Genome Res"},{"key":"2023020109013827400_btac046-B2","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.cell.2019.03.049","article-title":"Tracking five millennia of horse management with extensive ancient genome time series","volume":"177","author":"Fages","year":"2019","journal-title":"Cell"},{"key":"2023020109013827400_btac046-B3","doi-asserted-by":"crossref","first-page":"iyaa045","DOI":"10.1093\/genetics\/iyaa045","article-title":"Assessing the performance of qpAdm: a statistical tool for studying population admixture","volume":"217","author":"Harney","year":"2021","journal-title":"Genetics"},{"key":"2023020109013827400_btac046-B4","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1038\/s41467-018-05257-7","article-title":"A tutorial on how not to over-interpret STRUCTURE and ADMIXTURE bar plots","volume":"9","author":"Lawson","year":"2018","journal-title":"Nat. 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