{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:40:07Z","timestamp":1759563607240,"version":"3.37.3"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T00:00:00Z","timestamp":1643846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,12]]},"DOI":"10.1093\/bioinformatics\/btac054","type":"journal-article","created":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T20:15:04Z","timestamp":1643314504000},"page":"2377-2379","source":"Crossref","is-referenced-by-count":2,"title":["Srinivasan (1962\u20132021) in Bioinformatics and beyond"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1776-4096","authenticated-orcid":false,"given":"M Michael","family":"Gromiha","sequence":"first","affiliation":[{"name":"Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras , Chennai, Tamil Nadu 600036, India"}]},{"given":"Christine A","family":"Orengo","sequence":"additional","affiliation":[{"name":"Department of Structural and Molecular Biology, University College London , London WC1E 6BT, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6642-2367","authenticated-orcid":false,"given":"Ramanathan","family":"Sowdhamini","sequence":"additional","affiliation":[{"name":"National Centre for Biological Sciences (NCBS-TIFR), GKVK Campus , Bangalore, Karnataka 560065, India"},{"name":"Molecular Biophysics Unit, Indian Institute of Science , Bangalore 560012, India"},{"name":"Institute of Bioinformatics and Applied Biotechnology , Bangalore 560100, India"}]},{"given":"and Janet M","family":"Thornton","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus , Cambridge CB10 1SD, UK"}]}],"member":"286","published-online":{"date-parts":[[2022,2,3]]},"reference":[{"key":"2023020109015812200_btac054-B1","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1093\/nar\/gkv110","article-title":"The beta hairpin structure within ribosomal protein S5 mediates interplay between domains II and IV and regulates HCV IRES function","volume":"43","author":"Bhat","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"2023020109015812200_btac054-B2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1039\/D0MO00057D","article-title":"Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data","volume":"16","author":"Chakraborti","year":"2020","journal-title":"Mol. Omics"},{"key":"2023020109015812200_btac054-B3","doi-asserted-by":"crossref","first-page":"6830","DOI":"10.3390\/ijms22136830","article-title":"'All That Glitters Is Not Gold\u2019: high-resolution crystal structures of ligand-protein complexes need not always represent confident binding poses","volume":"22","author":"Chakraborti","year":"2021","journal-title":"Int. J. Mol. Sci"},{"key":"2023020109015812200_btac054-B4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10409239409086797","article-title":"Knowledge-based protein modelling","volume":"29","author":"Johnson","year":"1994","journal-title":"CRC Crit. Rev. Biochem. Mol. Biol"},{"key":"2023020109015812200_btac054-B5","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jsb.2016.07.012","article-title":"Use of evolutionary information in the fitting of atomic level protein models in low resolution cryo-EM map of a protein assembly improves the accuracy of the fitting","volume":"195","author":"Joseph","year":"2016","journal-title":"J. Struct. Biol"},{"key":"2023020109015812200_btac054-B6","doi-asserted-by":"crossref","first-page":"e1005975","DOI":"10.1371\/journal.pcbi.1005975","article-title":"Recognition of sites of functional specialisation in all known eukaryotic protein kinase families","volume":"14","author":"Kalaivani","year":"2018","journal-title":"PLoS Comput. Biol"},{"key":"2023020109015812200_btac054-B7","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-12-research0066","article-title":"The repertoire of protein kinases encoded in the draft version of the human genome: atypical variations and uncommon domain combinations","volume":"3","author":"Krupa","year":"2002","journal-title":"Genome Biol"},{"key":"2023020109015812200_btac054-B8","doi-asserted-by":"crossref","first-page":"D153","DOI":"10.1093\/nar\/gkh019","article-title":"KinG: a database of protein kinases in genomes","volume":"32","author":"Krupa","year":"2004","journal-title":"Nucleic Acids Res"},{"key":"2023020109015812200_btac054-B9","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.jmb.2004.04.043","article-title":"Structural modes of stabilization of permissive phosphorylation sites in protein kinases: distinct strategies in Ser\/Thr and Tyr kinases","volume":"339","author":"Krupa","year":"2004","journal-title":"J. Mol. Biol"},{"key":"2023020109015812200_btac054-B10","doi-asserted-by":"crossref","first-page":"bav060","DOI":"10.1093\/database\/bav060","article-title":"SInCRe-structural interactome computational resource for Mycobacterium tuberculosis","volume":"2015","author":"Metri","year":"2015","journal-title":"Database"},{"key":"2023020109015812200_btac054-B11","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jmb.2013.11.026","article-title":"Filling-in void and sparse regions in protein sequence space by protein-like artificial sequences enables remarkable enhancement in remote homology detection capability","volume":"426","author":"Mudgal","year":"2014","journal-title":"J. Mol. Biol"},{"key":"2023020109015812200_btac054-B12","doi-asserted-by":"crossref","first-page":"12231","DOI":"10.1074\/jbc.M210287200","article-title":"Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen","volume":"278","author":"Pudi","year":"2003","journal-title":"J. Biol. Chem"},{"key":"2023020109015812200_btac054-B13","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1080\/15476286.2016.1218590","article-title":"Structural and mechanistic insights into human splicing factor SF3b complex derived using an integrated approach guided by the cryo-EM density maps","volume":"13","author":"Rakesh","year":"2016","journal-title":"RNA Biol"},{"key":"2023020109015812200_btac054-B14","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/j.str.2019.09.009","article-title":"Stereochemical assessment of (\u03a6,\u03a8) outliers in protein structures using bond geometry-specific Ramachandran steric-maps","volume":"27","author":"Ravikumar","year":"2019","journal-title":"Structure"},{"key":"2023020109015812200_btac054-B15","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S0969-2126(94)00105-7","article-title":"Comparative analyses of pentraxins: implications for protomer assembly and ligand binding","volume":"2","author":"Srinivasan","year":"1994","journal-title":"Structure"},{"key":"2023020109015812200_btac054-B16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/(SICI)1097-0134(199610)26:2<217::AID-PROT11>3.0.CO;2-S","article-title":"Structural aspects of the functional modules in human protein kinase C\u03b1 deduced from comparative analyses","volume":"26","author":"Srinivasan","year":"1996","journal-title":"Proteins"},{"key":"2023020109015812200_btac054-B17","doi-asserted-by":"crossref","first-page":"9048","DOI":"10.1074\/jbc.RA118.006814","article-title":"Bioinformatic and mutational studies of related toxin\u2013antitoxin pairs in Mycobacterium tuberculosis predict and identify key functional residues","volume":"294","author":"Tandon","year":"2019","journal-title":"J. Biol. Chem"},{"key":"2023020109015812200_btac054-B18","doi-asserted-by":"crossref","first-page":"W473","DOI":"10.1093\/nar\/gkm423","article-title":"PIC: protein Interactions Calculator","volume":"35","author":"Tina","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"2023020109015812200_btac054-B19","doi-asserted-by":"crossref","first-page":"e1006008","DOI":"10.1371\/journal.pcbi.1006008","article-title":"Same but not alike: structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains","volume":"14","author":"Vishwanath","year":"2018","journal-title":"PLoS Comput. Biol"},{"key":"2023020109015812200_btac054-B20","doi-asserted-by":"crossref","first-page":"747344","DOI":"10.3389\/fgene.2021.747344","article-title":"Sequence divergence and functional specializations of the ancient spliceosomal SF3b: implications in flexibility and adaptations of the multi-protein complex","volume":"12","author":"Yazhini","year":"2022","journal-title":"Front. Genet"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/advance-article-pdf\/doi\/10.1093\/bioinformatics\/btac054\/42439681\/btac054.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/38\/8\/2377\/49008772\/btac054.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/38\/8\/2377\/49008772\/btac054.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T20:48:13Z","timestamp":1675284493000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/38\/8\/2377\/6520803"}},"subtitle":[],"editor":[{"given":"Alfonso","family":"Valencia","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2022,2,3]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,4,12]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btac054","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"type":"print","value":"1367-4803"},{"type":"electronic","value":"1367-4811"}],"subject":[],"published-other":{"date-parts":[[2022,4,15]]},"published":{"date-parts":[[2022,2,3]]}}}