{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T18:02:17Z","timestamp":1776189737632,"version":"3.50.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T00:00:00Z","timestamp":1649980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Deutsche Forschungsgemeinschaft (DFG, German Research Foundation"},{"name":"Germany\u2019s Excellence Strategy\u2014EXC","award":["2048\/1\u2013390686111"],"award-info":[{"award-number":["2048\/1\u2013390686111"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Third-generation genome sequencing technologies have led to a sharp increase in the number of high-quality genome assemblies. This allows the comparison of multiple assembled genomes of individual species and demands new tools for visualizing their structural properties. Here, we present plotsr, an efficient tool to visualize structural similarities and rearrangements between genomes. It can be used to compare genomes on chromosome level or to zoom in on any selected region. In addition, plotsr can augment the visualization with regional identifiers (e.g. genes or genomic markers) or histogram tracks for continuous features (e.g. GC content or polymorphism density).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and implementation<\/jats:title>\n                    <jats:p>plotsr is implemented as a python package and uses the standard matplotlib library for plotting. It is freely available under the MIT license at GitHub (https:\/\/github.com\/schneebergerlab\/plotsr) and bioconda (https:\/\/anaconda.org\/bioconda\/plotsr).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Supplementary information<\/jats:title>\n                    <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btac196","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T07:10:15Z","timestamp":1649920215000},"page":"2922-2926","source":"Crossref","is-referenced-by-count":269,"title":["plotsr: visualizing structural similarities and rearrangements between multiple genomes"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6087-6990","authenticated-orcid":false,"given":"Manish","family":"Goel","sequence":"first","affiliation":[{"name":"Faculty of Biology, LMU Munich , Planegg-Martinsried 82152, Germany"},{"name":"Department of Genetics, Faculty of Biology, LMU Munich , Germany"}]},{"given":"Korbinian","family":"Schneeberger","sequence":"additional","affiliation":[{"name":"Faculty of Biology, LMU Munich , Planegg-Martinsried 82152, Germany"},{"name":"Department of Genetics, Faculty of Biology, LMU Munich , Germany"}]}],"member":"286","published-online":{"date-parts":[[2022,4,15]]},"reference":[{"key":"2023020109125751000_btac196-B1","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/nature03001","article-title":"Finishing the euchromatic sequence of the human genome","volume":"431","author":"Abdellah","year":"2004","journal-title":"Nature"},{"key":"2023020109125751000_btac196-B2","doi-asserted-by":"crossref","first-page":"5318","DOI":"10.1093\/bioinformatics\/btz597","article-title":"Sequence tube maps: making graph genomes intuitive to commuters","volume":"35","author":"Beyer","year":"2019","journal-title":"Bioinformatics"},{"key":"2023020109125751000_btac196-B3","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13059-020-02235-5","article-title":"Gamete binning: chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes","volume":"21","author":"Campoy","year":"2020","journal-title":"Genome Biol"},{"key":"2023020109125751000_btac196-B4","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/s13059-019-1911-0","article-title":"SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies","volume":"20","author":"Goel","year":"2019","journal-title":"Genome Biol"},{"key":"2023020109125751000_btac196-B5","author":"Guarracino","year":"2021"},{"key":"2023020109125751000_btac196-B6","author":"Jarvis","year":"2022"},{"key":"2023020109125751000_btac196-B7","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/nbt.4277","article-title":"De novo assembly of haplotype-resolved genomes with trio binning","volume":"36","author":"Koren","year":"2018","journal-title":"Nat. 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