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ToxSTAR provides structural similarity-based DILI analysis and in-house DILI prediction models that predict four DILI subtypes (cholestasis, cirrhosis, hepatitis and steatosis) based on drug and drug metabolite molecules.<\/jats:p><\/jats:sec><jats:sec><jats:title>Availability and implementation<\/jats:title><jats:p>ToxSTAR is freely available at https:\/\/toxstar.kitox.re.kr\/.<\/jats:p><\/jats:sec><jats:sec><jats:title>Supplementary information<\/jats:title><jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p><\/jats:sec>","DOI":"10.1093\/bioinformatics\/btac490","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T13:43:36Z","timestamp":1659015816000},"page":"4426-4427","source":"Crossref","is-referenced-by-count":13,"title":["ToxSTAR: drug-induced liver injury prediction tool for the web environment"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3665-0841","authenticated-orcid":false,"given":"Hyun Kil","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"},{"name":"Department of Human and Environmental Toxicology, University of Science and Technology , 34113 Daejeon, Republic of Korea"}]},{"given":"Hang-Suk","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"}]},{"given":"Sangwoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"}]},{"given":"Se-Myo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"}]},{"given":"Daeui","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"},{"name":"Department of Human and Environmental Toxicology, University of Science and Technology , 34113 Daejeon, Republic of Korea"}]},{"given":"Myung-Gyun","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1610-5259","authenticated-orcid":false,"given":"Sungbo","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"}]},{"given":"Jung-Hwa","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"},{"name":"Department of Human and Environmental Toxicology, University of Science and Technology , 34113 Daejeon, Republic of Korea"}]},{"given":"Hyoung-Yun","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"},{"name":"Department of Human and Environmental Toxicology, University of Science and Technology , 34113 Daejeon, Republic of Korea"}]},{"given":"Woo-Keun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"},{"name":"Department of Human and Environmental Toxicology, University of Science and Technology , 34113 Daejeon, Republic of Korea"}]},{"given":"Seokjoo","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Predictive toxicology, Korea Institute of Toxicology , 34114 Daejeon, Republic of Korea"},{"name":"Department of Human and Environmental Toxicology, University of Science and Technology , 34113 Daejeon, Republic of Korea"}]}],"member":"286","published-online":{"date-parts":[[2022,7,28]]},"reference":[{"key":"2023041408234040200_","doi-asserted-by":"crossref","first-page":"W257","DOI":"10.1093\/nar\/gky318","article-title":"ProTox-II: a webserver for the prediction of toxicity of chemicals","volume":"46","author":"Banerjee","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"2023041408234040200_","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/978-3-030-16443-0_18","volume-title":"Advances in Computational Toxicology: Methodologies and Applications in Regulatory Science","author":"Benfenati","year":"2019"},{"key":"2023041408234040200_","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1758-2946-5-24","article-title":"JSME: a free molecule editor in JavaScript","volume":"5","author":"Bienfait","year":"2013","journal-title":"J. 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