{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T14:56:14Z","timestamp":1775055374064,"version":"3.50.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union on the Guadeloupe Region"},{"name":"European Research and Development Funds","award":["2018-FED-1084"],"award-info":[{"award-number":["2018-FED-1084"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Motivation<\/jats:title><jats:p>As pan-genome approaches are largely employed for bacterial comparative genomics and evolution analyses, but still difficult to be carried out by non-bioinformatician biologists, there is a need for an innovative tool facilitating the exploration of bacterial pan-genomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PanExplorer is a web application providing various genomic analyses and reports, giving intuitive views that enable a better understanding of bacterial pan-genomes. As an example, we produced the pan-genome for 121 Anaplasmataceae strains (including 30 Ehrlichia, 15 Anaplasma, 68 Wolbachia).<\/jats:p><\/jats:sec><jats:sec><jats:title>Availability and implementation<\/jats:title><jats:p>PanExplorer is written in Perl CGI and relies on several JavaScript libraries for visualization (hotmap.js, MauveViewer, CircosJS). It is freely available at http:\/\/panexplorer.southgreen.fr. The source code has been released in a GitHub repository https:\/\/github.com\/SouthGreenPlatform\/PanExplorer. A documentation section is available on PanExplorer website.<\/jats:p><\/jats:sec>","DOI":"10.1093\/bioinformatics\/btac504","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T15:45:59Z","timestamp":1659455159000},"page":"4412-4414","source":"Crossref","is-referenced-by-count":65,"title":["PanExplorer: a web-based tool for exploratory analysis and visualization of bacterial pan-genomes"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8120-8409","authenticated-orcid":false,"given":"Alexis","family":"Dereeper","sequence":"first","affiliation":[{"name":"CIRAD, UMR ASTRE , F-97170 Petit-Bourg, France"},{"name":"French Institute of Bioinformatics (IFB)\u2014South Green Bioinformatics Platform, Bioversity, CIRAD, INRAE, IRD , F-34398 Montpellier, France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9308-974X","authenticated-orcid":false,"given":"Marilyne","family":"Summo","sequence":"additional","affiliation":[{"name":"French Institute of Bioinformatics (IFB)\u2014South Green Bioinformatics Platform, Bioversity, CIRAD, INRAE, IRD , F-34398 Montpellier, France"},{"name":"CIRAD, UMR AGAP , F-34398 Montpellier, France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2735-176X","authenticated-orcid":false,"given":"Damien F","family":"Meyer","sequence":"additional","affiliation":[{"name":"CIRAD, UMR ASTRE , F-97170 Petit-Bourg, France"}]}],"member":"286","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"2023041408242450000_","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1109\/TVCG.2011.185","article-title":"D3: data-driven documents","volume":"17","author":"Bostock","year":"2011","journal-title":"IEEE Trans. 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