{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:22:56Z","timestamp":1780341776902,"version":"3.54.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"22","license":[{"start":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T00:00:00Z","timestamp":1664841600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Rijk Zwaan Breeding B.V."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Motivation<\/jats:title><jats:p>Multi-parent populations (MPPs) are popular for QTL mapping because they combine wide genetic diversity in parents with easy control of population structure, but a limited number of software tools for QTL mapping are specifically developed for general MPP designs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We developed an R package called statgenMPP, adopting a unified identity-by-descent (IBD)-based mixed model approach for QTL analysis in MPPs. The package offers easy-to-use functionalities of IBD calculations, mixed model solutions and visualizations for QTL mapping in a wide range of MPP designs, including diallele, nested-association mapping populations, multi-parent advanced genetic inter-cross populations and other complicated MPPs with known crossing schemes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Availability and implementation<\/jats:title><jats:p>The R package statgenMPP is open-source and freely available on CRAN at https:\/\/CRAN.R-project.org\/package=statgenMPP<\/jats:p><\/jats:sec><jats:sec><jats:title>Supplementary information<\/jats:title><jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p><\/jats:sec>","DOI":"10.1093\/bioinformatics\/btac662","type":"journal-article","created":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T13:26:39Z","timestamp":1664803599000},"page":"5134-5136","source":"Crossref","is-referenced-by-count":11,"title":["<i>statgenMPP<\/i>: an R package implementing an IBD-based mixed model approach for QTL mapping in a wide range of multi-parent populations"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5719-5775","authenticated-orcid":false,"given":"Wenhao","family":"Li","sequence":"first","affiliation":[{"name":"Biometris, Wageningen University and Research Center , Wageningen, 6700 AC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin P","family":"Boer","sequence":"additional","affiliation":[{"name":"Biometris, Wageningen University and Research Center , Wageningen, 6700 AC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart-Jan","family":"van Rossum","sequence":"additional","affiliation":[{"name":"Biometris, Wageningen University and Research Center , Wageningen, 6700 AC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6030-3933","authenticated-orcid":false,"given":"Chaozhi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Biometris, Wageningen University and Research Center , Wageningen, 6700 AC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronny V L","family":"Joosen","sequence":"additional","affiliation":[{"name":"Rijk Zwaan Breeding B.V. , De Lier 2678 ZG, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred A","family":"van Eeuwijk","sequence":"additional","affiliation":[{"name":"Biometris, Wageningen University and Research Center , Wageningen, 6700 AC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,10,4]]},"reference":[{"key":"2022112014191096900_btac662-B1","first-page":"229","article-title":"The dawn of the age of multi-parent magic populations in plant breeding: novel powerful next-generation resources for genetic analysis and selection of recombinant elite material","volume":"9","author":"Arrones","year":"2020","journal-title":"Biology (Basel)"},{"key":"2022112014191096900_btac662-B2","author":"Boer","year":"2021"},{"key":"2022112014191096900_btac662-B3","author":"Boer","year":"2021"},{"key":"2022112014191096900_btac662-B4","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1534\/genetics.109.110304","article-title":"Genetic control of photoperiod sensitivity in maize revealed by joint multiple population analysis","volume":"184","author":"Coles","year":"2010","journal-title":"Genetics"},{"key":"2022112014191096900_btac662-B5","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1111\/pbi.12504","article-title":"A highly recombined, high-density, eight-founder wheat MAGIC map reveals extensive segregation distortion and genomic locations of introgression segments","volume":"14","author":"Gardner","year":"2016","journal-title":"Plant Biotechnol. 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