{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T14:53:47Z","timestamp":1782226427910,"version":"3.54.5"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon 2020 Research and Innovation Programme","award":["945151"],"award-info":[{"award-number":["945151"]}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>Accurate clustering of mixed data, encompassing binary, categorical, and continuous variables, is vital for effective patient stratification in clinical questionnaire analysis. To address this need, we present longmixr, a comprehensive R package providing a robust framework for clustering mixed longitudinal data using finite mixture modeling techniques. By incorporating consensus clustering, longmixr ensures reliable and stable clustering results. Moreover, the package includes a detailed vignette that facilitates cluster exploration and visualization.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>The R package is freely available at https:\/\/cran.r-project.org\/package=longmixr with detailed documentation, including a case vignette, at https:\/\/cellmapslab.github.io\/longmixr\/.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btae137","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T23:12:19Z","timestamp":1710371539000},"source":"Crossref","is-referenced-by-count":6,"title":["longmixr: a tool for robust clustering of high-dimensional cross-sectional and longitudinal variables of mixed data types"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1849-1106","authenticated-orcid":false,"given":"Jonas","family":"Hagenberg","sequence":"first","affiliation":[{"name":"Max Planck Institute of Psychiatry , 80804 Munich, Germany"},{"name":"International Max Planck Research School for Translational Psychiatry , 80804 Munich, Germany"},{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen , 85764 Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Budde","sequence":"additional","affiliation":[{"name":"Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich , 80336 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teodora","family":"Pandeva","sequence":"additional","affiliation":[{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen , 85764 Neuherberg, Germany"},{"name":"AI4Science, AMLab, University of Amsterdam , GH 1090 Amsterdam, The Netherlands"},{"name":"Swammerdam Institute for Life Sciences, University of Amsterdam , GE 1090 Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Kondofersky","sequence":"additional","affiliation":[{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen , 85764 Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina K","family":"Schaupp","sequence":"additional","affiliation":[{"name":"Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich , 80336 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian J","family":"Theis","sequence":"additional","affiliation":[{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen , 85764 Neuherberg, Germany"},{"name":"Department of Mathematics, Technical University of Munich , 85748 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G","family":"Schulze","sequence":"additional","affiliation":[{"name":"Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich , 80336 Munich, Germany"},{"name":"Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University , Syracuse, NY 13210, United States"},{"name":"Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine , Baltimore, MD 21287, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikola S","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen , 85764 Neuherberg, 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