{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:28:16Z","timestamp":1773124096460,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T00:00:00Z","timestamp":1727481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"CNDD Genomics and BioinformaticsCore","award":["P20 GM148302"],"award-info":[{"award-number":["P20 GM148302"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Motivation<\/jats:title>\n                  <jats:p>The scToppR package provides a ToppGene interface from R programs\/scripts to fully access\/control the database for functional enrichment without the need for active interaction on its Web site (https:\/\/toppgene.cchmc.org\/).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The library facilitates the functional enrichment analysis and visualization by interacting with ToppGene, downloading the functional enrichment dataframes, and using R environment to visualize the final results.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>Code and documentation are currently available at https:\/\/github.com\/BioinformaticsMUSC\/scToppR<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btae582","type":"journal-article","created":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T17:32:17Z","timestamp":1727544737000},"source":"Crossref","is-referenced-by-count":8,"title":["scToppR: a coding-friendly R interface to ToppGene"],"prefix":"10.1093","volume":"40","author":[{"given":"Bryan","family":"Granger","sequence":"first","affiliation":[{"name":"Bioinformatics Core, Department of Neuroscience, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9028-9458","authenticated-orcid":false,"given":"Stefano","family":"Berto","sequence":"additional","affiliation":[{"name":"Neurogenomics Laboratory, Department of Neuroscience, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}]}],"member":"286","published-online":{"date-parts":[[2024,9,28]]},"reference":[{"key":"2024111117055134800_btae582-B1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene Ontology: tool for the unification of biology. 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