{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T13:34:53Z","timestamp":1786368893059,"version":"3.56.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: The occurrence of false positives and false negatives in a microarray analysis could be easily estimated if the distribution of p-values were approximated and then expressed as a mixture of null and alternative densities. Essentially any distribution of p-values can be expressed as such a mixture by extracting a uniform density from it.<\/jats:p>\n               <jats:p>Results: The occurrence of false positives and false negatives in a microarray analysis could be easily estimated if the distribution of p-values were approximated and then expressed as a mixture of null and alternative densities. Essentially any distribution of p-values can be expressed as such a mixture by extracting a uniform density from it.<\/jats:p>\n               <jats:p>Availability: An S-plus function library is available from http:\/\/www.stjuderesearch.org\/statistics<\/jats:p>\n               <jats:p>Contact: stanley.pounds@stjude.org<\/jats:p>\n               <jats:p>* To whom correspondence should be addressed.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btg148","type":"journal-article","created":{"date-parts":[[2003,6,30]],"date-time":"2003-06-30T23:09:17Z","timestamp":1057014557000},"page":"1236-1242","source":"Crossref","is-referenced-by-count":324,"title":["Estimating the occurrence of false positives and false\nnegatives in microarray studies by approximating and\npartitioning the empirical distribution of <i>p<\/i>-values"],"prefix":"10.1093","volume":"19","author":[{"given":"Stan","family":"Pounds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan W.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2003,7,1]]},"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/19\/10\/1236\/48903778\/bioinformatics_19_10_1236.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/19\/10\/1236\/48903778\/bioinformatics_19_10_1236.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T15:50:19Z","timestamp":1674661819000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/19\/10\/1236\/184434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,1]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2003,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btg148","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2003,7,1]]},"published":{"date-parts":[[2003,7,1]]}}}