{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T21:45:29Z","timestamp":1757540729483},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: GRIL is a tool to automatically identify collinear regions in a set of bacterial-size genome sequences. GRIL uses three basic steps. First, regions of high sequence identity are located. Second, some of these regions are filtered based on user-specified criteria. Finally, the remaining regions of sequence identity are used to define significant collinear regions among the sequences. By locating collinear regions of sequence, GRIL provides a basis for multiple genome alignment using current alignment systems. GRIL also provides a basis for using current inversion distance tools to infer phylogeny.<\/jats:p>\n               <jats:p>Availability: GRIL is implemented in C++ and runs on any x86-based Linux or Windows platform. It is available from http:\/\/asap.ahabs.wisc.edu\/gril<\/jats:p>\n               <jats:p>Supplementary information: The GRIL web site contains a detailed description of the GRIL's algorithms, an example of applying GRIL to five genomes, and verification of the correctness of the results.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btg378","type":"journal-article","created":{"date-parts":[[2003,12,23]],"date-time":"2003-12-23T16:57:44Z","timestamp":1072198664000},"page":"122-124","source":"Crossref","is-referenced-by-count":25,"title":["GRIL: genome rearrangement and inversion locator"],"prefix":"10.1093","volume":"20","author":[{"given":"Aaron E.","family":"Darling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bob","family":"Mau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick R.","family":"Blattner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole T.","family":"Perna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,1,1]]},"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/20\/1\/122\/48905165\/bioinformatics_20_1_122.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/20\/1\/122\/48905165\/bioinformatics_20_1_122.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T18:47:17Z","timestamp":1674672437000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/20\/1\/122\/228948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btg378","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2004,1,1]]},"published":{"date-parts":[[2004,1,1]]}}}