{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:22:14Z","timestamp":1767374534607},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,3,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Association studies may request more details of a specific haplotype. Haplotype-specific decay of linkage disequilibrium is such a crucial and versatile characteristic. It may be used, e.g. to search for signals of natural selection in a risk haplotype. Here, we present a web-based tool to explore the relationship between population frequency and extended linkage disequilibrium measured as haplotype homozygosity of observed haplotypes within a specified candidate region.<\/jats:p>\n               <jats:p>Availability: The web-tool is available at http:\/\/ihg.gsf.de\/cgi-bin\/mueller\/webehh.pl<\/jats:p>","DOI":"10.1093\/bioinformatics\/btg481","type":"journal-article","created":{"date-parts":[[2004,3,2]],"date-time":"2004-03-02T21:41:06Z","timestamp":1078263666000},"page":"786-787","source":"Crossref","is-referenced-by-count":14,"title":["Plotting haplotype-specific linkage disequilibrium patterns by extended haplotype homozygosity"],"prefix":"10.1093","volume":"20","author":[{"given":"Jakob C.","family":"Mueller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Andreoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,2,5]]},"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/20\/5\/786\/48905389\/bioinformatics_20_5_786.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/20\/5\/786\/48905389\/bioinformatics_20_5_786.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T18:01:59Z","timestamp":1674669719000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/20\/5\/786\/214052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2,5]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,3,22]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btg481","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2004,3,22]]},"published":{"date-parts":[[2004,2,5]]}}}