{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:09:00Z","timestamp":1773274140390,"version":"3.50.1"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,12,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity. This provides a tool for the statistical analysis of both empirical data and methods designed to detect natural selection.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/www.stats.ox.ac.uk\/mathgen\/software.html<\/jats:p>\n               <jats:p>Supplementary information: \u00a0http:\/\/www.stats.ox.ac.uk\/mathgen\/software.html<\/jats:p>","DOI":"10.1093\/bioinformatics\/bth417","type":"journal-article","created":{"date-parts":[[2004,7,24]],"date-time":"2004-07-24T01:27:46Z","timestamp":1090632466000},"page":"3673-3675","source":"Crossref","is-referenced-by-count":89,"title":["SelSim: a program to simulate population genetic data with natural selection and recombination"],"prefix":"10.1093","volume":"20","author":[{"given":"Chris C. A.","family":"Spencer","sequence":"first","affiliation":[{"name":"Department of Statistics, 1 South Parks Road, Oxford OX1 3TG, UK"}]},{"given":"Graham","family":"Coop","sequence":"additional","affiliation":[{"name":"Department of Statistics, 1 South Parks Road, Oxford OX1 3TG, UK"}]}],"member":"286","published-online":{"date-parts":[[2004,7,22]]},"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/20\/18\/3673\/48906627\/bioinformatics_20_18_3673.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/20\/18\/3673\/48906627\/bioinformatics_20_18_3673.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T17:03:42Z","timestamp":1674666222000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/20\/18\/3673\/202257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7,22]]},"references-count":0,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2004,12,12]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/bth417","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2004,12,12]]},"published":{"date-parts":[[2004,7,22]]}}}