{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T09:03:22Z","timestamp":1772269402410,"version":"3.50.1"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: DNAFSMiner (DNA Functional Sites Miner) is a web-based software toolbox to recognize functional sites in nucleic acid sequences. Currently in this toolbox, we provide two software: TIS Miner and Poly(A) Signal Miner. The TIS Miner can be used to predict translation initiation sites in vertebrate DNA\/mRNA\/cDNA sequences, and the Poly(A) Signal Miner can be used to predict polyadenylation [poly(A)] signals in human DNA sequences. The prediction results are better than those by literature methods on two benchmark applications. This good performance is mainly attributable to our unique learning method. DNAFSMiner is available free of charge for academic and non-profit organizations.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/research.i2r.a-star.edu.sg\/DNAFSMiner\/<\/jats:p>\n               <jats:p>Contact: \u00a0huiqing@i2r.a-star.edu.sg<\/jats:p>","DOI":"10.1093\/bioinformatics\/bth437","type":"journal-article","created":{"date-parts":[[2004,7,30]],"date-time":"2004-07-30T00:17:42Z","timestamp":1091146662000},"page":"671-673","source":"Crossref","is-referenced-by-count":42,"title":["DNAFSMiner: a web-based software toolbox to recognize two types of functional sites in DNA sequences"],"prefix":"10.1093","volume":"21","author":[{"given":"Huiqing","family":"Liu","sequence":"first","affiliation":[{"name":"Institute for Infocomm Research 21 Heng Mui Keng Terrace, Singapore, 119613"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Han","sequence":"additional","affiliation":[{"name":"Institute for Infocomm Research 21 Heng Mui Keng Terrace, Singapore, 119613"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinyan","family":"Li","sequence":"additional","affiliation":[{"name":"Institute for Infocomm Research 21 Heng Mui Keng Terrace, Singapore, 119613"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Limsoon","family":"Wong","sequence":"additional","affiliation":[{"name":"Institute for Infocomm Research 21 Heng Mui Keng Terrace, Singapore, 119613"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,7,29]]},"reference":[{"key":"2023013107223247400_B1","doi-asserted-by":"crossref","unstructured":"Kozak, M. 1987An analysis of 5\u2032-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res.158125\u20138148","DOI":"10.1093\/nar\/15.20.8125"},{"key":"2023013107223247400_B2","doi-asserted-by":"crossref","unstructured":"Legendre, M. and Gautheret, D. 2003Sequence determinants in human polyadenylation site selection. BMC Genomics47","DOI":"10.1186\/1471-2164-4-7"},{"key":"2023013107223247400_B3","unstructured":"Liu, H., Han, H., Li, J., Wong, L. 2003An in-silico method for prediction of polyadenylation signals in human sequences. Proceedings of 14th International Conference on Genome Informatics (GIW 2003) ,  pp. 84\u201393"},{"key":"2023013107223247400_B4","unstructured":"Liu, H., Han, H., Li, J., Wong, L. 2004Using amino acid patterns to accurately predict translation initiation sites. In-Silico Biol.40022http:\/\/www.bioinfo.de\/isb\/2004\/04\/0022\/"},{"key":"2023013107223247400_B5","unstructured":"Liu, H. and Wong, L. 2003Data mining tools for biological sequences. J. Bioinform. Comput. Biol.1139\u2013168"},{"key":"2023013107223247400_B6","doi-asserted-by":"crossref","unstructured":"Salamov, A.A., Nishikawa, T., Swindells, M.A. 1998Assessing protein coding region integrity in cDNA sequencing projects. Bioinformatics14384\u2013390","DOI":"10.1093\/bioinformatics\/14.5.384"},{"key":"2023013107223247400_B7","unstructured":"Tabaska, J.E. and Zhang, M.Q. 1999Detection of polyadenylation signals in human DNA sequences. Gene23177\u201386"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/21\/5\/671\/48962378\/bioinformatics_21_5_671.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/21\/5\/671\/48962378\/bioinformatics_21_5_671.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T09:47:08Z","timestamp":1675158428000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/21\/5\/671\/219843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7,29]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/bth437","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,3,1]]},"published":{"date-parts":[[2004,7,29]]}}}