{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T22:53:34Z","timestamp":1762296814453},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"suppl_1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: For the purpose of identifying evolutionary reticulation events in flowering plants, we determine a large number of paired, conserved DNA oligomers that may be used as primers to amplify orthologous DNA regions using the polymerase chain reaction (PCR).<\/jats:p>\n               <jats:p>Results: We develop an initial candidate set by comparing the Arabidopsis and rice genomes using MoBIoS (Molecular Biological Information System). MoBIoS is a metric-space database management system targeting life science data. Through the use of metric-space indexing techniques, two genomes can be compared in O(mlog n), where m and n are the lengths of the genomes, versus O(mn) for BLAST-based analysis. The filtering of low-complexity regions may also be accomplished by directly assessing the uniqueness of the region. We describe mSQL, a SQL extension being developed for MoBIoS that encapsulates the algorithmic details in a common database programming language, shielding end-users from esoteric programming.<\/jats:p>\n               <jats:p>Availability: Available upon request from authors.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bth929","type":"journal-article","created":{"date-parts":[[2004,7,19]],"date-time":"2004-07-19T17:07:37Z","timestamp":1090256857000},"page":"i355-i362","source":"Crossref","is-referenced-by-count":14,"title":["Using MoBIoS' scalable genome join to find conserved primer pair candidates between two genomes"],"prefix":"10.1093","volume":"20","author":[{"given":"Weijia","family":"Xu","sequence":"first","affiliation":[]},{"given":"Willard J.","family":"Briggs","sequence":"additional","affiliation":[]},{"given":"Joanna","family":"Padolina","sequence":"additional","affiliation":[]},{"given":"Ruth E.","family":"Timme","sequence":"additional","affiliation":[]},{"given":"Wenguo","family":"Liu","sequence":"additional","affiliation":[]},{"given":"C. Randal","family":"Linder","sequence":"additional","affiliation":[]},{"given":"Daniel P.","family":"Miranker","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2004,8,4]]},"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/20\/suppl_1\/i355\/217562","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/20\/suppl_1\/i355\/217562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T05:39:21Z","timestamp":1688362761000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/20\/suppl_1\/i355\/217562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8,4]]},"references-count":0,"journal-issue":{"issue":"suppl_1","published-print":{"date-parts":[[2004,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/bth929","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2004,8,4]]},"published":{"date-parts":[[2004,8,4]]}}}