{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T21:15:17Z","timestamp":1722892517267},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Several methods for establishing cross-links between Protein Data Bank (PDB) structures or Structural Classification of Proteins (SCOP) domains and Swiss-Prot + TrEMBL sequences (or vice versa) rely on database annotations. Alternatively, sequence alignment procedures can be used. In this study, we describe Seq2Struct, a web resource for the identification of sequence-structure links. The resource consists of an exhaustive collection of annotated links between Swiss-Prot + TrEMBL and PDB + SCOP database entries. Links are based on pre-established highly reliable thresholds and stored in a relational database, which has been enhanced using annotations derived from Swiss-Prot, PDB, SCOP, GOA and DSSP databases. The Seq2Struct database contents, supported by a WWW web interface, can be queried both online and downloaded.<\/jats:p>\n               <jats:p>Availability: The Seq2Struct resource, with related documentation, is available at http:\/\/surface.bio.uniroma2.it\/seq2struct\/<\/jats:p>\n               <jats:p>Contact: \u00a0seq2struct@cbm.bio.uniroma2.it<\/jats:p>","DOI":"10.1093\/bioinformatics\/bti049","type":"journal-article","created":{"date-parts":[[2004,9,29]],"date-time":"2004-09-29T01:27:46Z","timestamp":1096421266000},"page":"551-553","source":"Crossref","is-referenced-by-count":9,"title":["Seq2Struct: a resource for establishing sequence-structure links"],"prefix":"10.1093","volume":"21","author":[{"given":"Allegra","family":"Via","sequence":"first","affiliation":[{"name":"Department of Biology, Centre for Molecular Bioinformatics, University of Rome Tor Vergata 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Zanzoni","sequence":"additional","affiliation":[{"name":"Department of Biology, Centre for Molecular Bioinformatics, University of Rome Tor Vergata 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Helmer-Citterich","sequence":"additional","affiliation":[{"name":"Department of Biology, Centre for Molecular Bioinformatics, University of Rome Tor Vergata 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,9,28]]},"reference":[{"key":"2023013107235374200_B1","doi-asserted-by":"crossref","unstructured":"Altschul, S.F., Madden, T.L., Schaffer, A.A., Zhang, J., Zhang, Z., Miller, W., Lipman, D.J. 1997Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. 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