{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:14:31Z","timestamp":1787008471103,"version":"build-2736575974"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Summary: MicroRNAs (miRNAs) are a recently discovered class of non-coding RNAs that regulate gene and protein expression in plants and animals. MiRNAs have so far been identified mostly by specific cloning of small RNA molecules, complemented by computational methods. We present a computational identification approach that is able to identify candidate miRNA homologs in any set of sequences, given a query miRNA. The approach is based on a sequence similarity search step followed by a set of structural filters.<\/jats:p>\n                  <jats:p>Availability: microHARVESTER is offered as a web-service and additionally as source code upon request at<\/jats:p>\n                  <jats:p>Contact: \u00a0dezulian@informatik.uni-tuebingen.de<\/jats:p>","DOI":"10.1093\/bioinformatics\/bti802","type":"journal-article","created":{"date-parts":[[2005,11,29]],"date-time":"2005-11-29T22:18:43Z","timestamp":1133302723000},"page":"359-360","source":"Crossref","is-referenced-by-count":114,"title":["Identification of plant microRNA homologs"],"prefix":"10.1093","volume":"22","author":[{"given":"Tobias","family":"Dezulian","sequence":"first","affiliation":[{"name":"Center for Bioinformatics T\u00fcbingen, T\u00fcbingen University 1 \u00a0 1 \u00a0 \u00a0 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Remmert","sequence":"additional","affiliation":[{"name":"Center for Bioinformatics T\u00fcbingen, T\u00fcbingen University 1 \u00a0 1 \u00a0 \u00a0 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier F.","family":"Palatnik","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Developmental Biology, T\u00fcbingen 2 \u00a0 2 \u00a0 \u00a0 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlef","family":"Weigel","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Developmental Biology, T\u00fcbingen 2 \u00a0 2 \u00a0 \u00a0 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel H.","family":"Huson","sequence":"additional","affiliation":[{"name":"Center for Bioinformatics T\u00fcbingen, T\u00fcbingen University 1 \u00a0 1 \u00a0 \u00a0 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,11,29]]},"reference":[{"key":"2023012408330852300_b1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1101\/gr.2908205","article-title":"Computational prediction of miRNAs in Arabidopsis thaliana","volume":"15","author":"Adai","year":"2005","journal-title":"Genome Res."},{"key":"2023012408330852300_b2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cell.2005.04.004","article-title":"microRNA-directed phasing during trans-acting siRNA biogenesis in plants","volume":"121","author":"Allen","year":"2005","journal-title":"Cell"},{"key":"2023012408330852300_b3","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"2023012408330852300_b4","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1105\/tpc.105.032185","article-title":"Antiquity of MicroRNAs and their targets in land plants","volume":"17","author":"Axtell","year":"2005","journal-title":"Plant Cell"},{"key":"2023012408330852300_b5","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"2023012408330852300_b6","doi-asserted-by":"crossref","first-page":"D109","DOI":"10.1093\/nar\/gkh023","article-title":"The microRNA Registry","volume":"32","author":"Griffiths-Jones","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"2023012408330852300_b7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nrg1379","article-title":"MicroRNAs: small RNAs with a big role in gene regulation","volume":"5","author":"He","year":"2004","journal-title":"Nat. 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