{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T18:52:38Z","timestamp":1761418358093},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The visualization-aided exploration of complex datasets will allow the research community to formulate novel functional hypotheses leading to a better understanding of biological processes at all levels. Therefore, we have developed a web resource termed VIS-O-BAC designed for the functional investigation of expression data for model systems, such as bacterial pathogens based on a graphical display. Genome-scale datasets derived from typical \u2018omic\u2019 approaches can directly be explored with respect to three biologically relevant aspects, the genome structure (operon organization), the organization of genes in pathways (KEGG) and the gene function with Gene Ontology (GO) terms. The integrated viewers can be used in parallel and combine expression data and functional annotations from different external data repositories. The graphical visualizations evidently accelerate both the validation of regulatory information and the detection of affected biological processes.<\/jats:p>\n               <jats:p>Availability: \u00a0<\/jats:p>\n               <jats:p>Contact: \u00a0lja@gbf.de<\/jats:p>\n               <jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bti814","type":"journal-article","created":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T01:43:34Z","timestamp":1134092614000},"page":"630-631","source":"Crossref","is-referenced-by-count":3,"title":["VIS-O-BAC: exploratory visualization of functional genome studies from bacteria"],"prefix":"10.1093","volume":"22","author":[{"given":"Guido","family":"Dieterich","sequence":"first","affiliation":[{"name":"Department of Cell Biology, Research Centre for Biotechnology (GBF) \u00a0 Mascheroder Weg 1, 38124 Braunschweig, Germany"}]},{"given":"Uwe","family":"K\u00e4rst","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, Research Centre for Biotechnology (GBF) \u00a0 Mascheroder Weg 1, 38124 Braunschweig, Germany"}]},{"given":"J\u00fcrgen","family":"Wehland","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, Research Centre for Biotechnology (GBF) \u00a0 Mascheroder Weg 1, 38124 Braunschweig, Germany"}]},{"given":"Lothar","family":"J\u00e4nsch","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, Research Centre for Biotechnology (GBF) \u00a0 Mascheroder Weg 1, 38124 Braunschweig, Germany"}]}],"member":"286","published-online":{"date-parts":[[2005,12,8]]},"reference":[{"key":"2023012408525078100_b1","doi-asserted-by":"crossref","first-page":"D154","DOI":"10.1093\/nar\/gki070","article-title":"The Universal Protein Resource (UniProt)","volume":"33","author":"Bairoch","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"2023012408525078100_b2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1093\/nar\/29.1.126","article-title":"Genomes OnLine Database (GOLD): a monitor of genome projects world-wide","volume":"29","author":"Bernal","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"2023012408525078100_b3","doi-asserted-by":"crossref","first-page":"3710","DOI":"10.1093\/bioinformatics\/bth456","article-title":"GO::TermFinder\u2014open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes","volume":"20","author":"Boyle","year":"2004","journal-title":"Bioinformatics"},{"key":"2023012408525078100_b4","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1093\/bioinformatics\/bti528","article-title":"MineBlast: a literature presentation service supporting protein annotation by data mining of BLAST results","volume":"21","author":"Dieterich","year":"2005","journal-title":"Bioinformatics"},{"key":"2023012408525078100_b5","doi-asserted-by":"crossref","first-page":"D334","DOI":"10.1093\/nar\/gki108","article-title":"EcoCyc: a comprehensive database resource for Escherichia coli","volume":"33","author":"Keseler","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"2023012408525078100_b6","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1042\/BC20040155","article-title":"There's no place like WormBase: an indispensable resource for Caenorhabditis elegans researchers","volume":"97","author":"O'Connell","year":"2005","journal-title":"Biol. 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