{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T06:17:25Z","timestamp":1776406645146,"version":"3.51.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Biologists and other scientists routinely need to know times of divergence between species and to construct phylogenies calibrated to time (timetrees). Published studies reporting time estimates from molecular data have been increasing rapidly, but the data have been largely inaccessible to the greater community of scientists because of their complexity. TimeTree brings these data together in a consistent format and uses a hierarchical structure, corresponding to the tree of life, to maximize their utility. Results are presented and summarized, allowing users to quickly determine the range and robustness of time estimates and the degree of consensus from the published literature.<\/jats:p>\n               <jats:p>Availability: TimeTree is available at<\/jats:p>\n               <jats:p>Contact: \u00a0sbh1@psu.edu<\/jats:p>","DOI":"10.1093\/bioinformatics\/btl505","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T00:45:58Z","timestamp":1160009158000},"page":"2971-2972","source":"Crossref","is-referenced-by-count":1086,"title":["TimeTree: a public knowledge-base of divergence times among organisms"],"prefix":"10.1093","volume":"22","author":[{"given":"S. Blair","family":"Hedges","sequence":"first","affiliation":[{"name":"Department of Biology, Pennsylvania State University 1 \u00a0 1 \u00a0 \u00a0 University Park, PA 16802-5301, USA"}]},{"given":"Joel","family":"Dudley","sequence":"additional","affiliation":[{"name":"Center for Evolutionary Functional Genomics, The Biodesign Institute and the School of Life Sciences 2 \u00a0 2 \u00a0 \u00a0 Arizona State University, Tempe, AZ 85287-5301, USA"}]},{"given":"Sudhir","family":"Kumar","sequence":"additional","affiliation":[{"name":"Center for Evolutionary Functional Genomics, The Biodesign Institute and the School of Life Sciences 2 \u00a0 2 \u00a0 \u00a0 Arizona State University, Tempe, AZ 85287-5301, USA"}]}],"member":"286","published-online":{"date-parts":[[2006,10,4]]},"reference":[{"key":"2023012409391886400_b1","volume-title":"The Fossil Record 2","author":"Benton","year":"1993"},{"key":"2023012409391886400_b2","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1371\/journal.pbio.0040088","article-title":"Relaxed phylogenetics and dating with confidence","volume":"4","author":"Drummond","year":"2006","journal-title":"PLoS Biol."},{"key":"2023012409391886400_b3","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/nrg929","article-title":"The origin and evolution of model organisms","volume":"3","author":"Hedges","year":"2002","journal-title":"Nat. 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