{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:58:00Z","timestamp":1775303880868,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: Chromatin-remodeling is an important event in the eukaryotic nucleus rendering nucleosomal DNA accessible for various transaction processes. Remodeling Factors facilitate the dynamic nature of chromatin through participation of the collective action of (i) ATP and (ii) Non-ATP dependent factors. Considering the importance of these factors in eukaryotes, we have developed, CREMOFAC, a dedicated and frequently updated web-database for chromatin-remodeling factors.<\/jats:p>\n               <jats:p>Results: The database harbors factors from 49 different organisms reported in literature and facilitates a comprehensive search for them. In addition, it also provides in-depth information for the factors reported in the three widely studied mammals namely, human, mouse and rat. Further, information on literature, pathways and phylogenetic relationships has also been covered. The development of CREMOFAC as a central repository for chromatin-remodeling factors and the absence of such a pre-existing database heighten its utility thus making its presence indispensable.<\/jats:p>\n               <jats:p>Availability: \u00a0<\/jats:p>\n               <jats:p>Contact: \u00a0mrsrao@jncasr.ac.in<\/jats:p>","DOI":"10.1093\/bioinformatics\/btl509","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T00:45:58Z","timestamp":1160009158000},"page":"2940-2944","source":"Crossref","is-referenced-by-count":17,"title":["CREMOFAC\u2014a database of chromatin remodeling factors"],"prefix":"10.1093","volume":"22","author":[{"given":"Agrawal","family":"Shipra","sequence":"first","affiliation":[{"name":"Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) 1 \u00a0 1 \u00a0 \u00a0 Jakkur, Bangalore 560064, India"}]},{"given":"Kumar","family":"Chetan","sequence":"additional","affiliation":[{"name":"Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) 1 \u00a0 1 \u00a0 \u00a0 Jakkur, Bangalore 560064, India"}]},{"given":"M. R. S.","family":"Rao","sequence":"additional","affiliation":[{"name":"Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) 1 \u00a0 1 \u00a0 \u00a0 Jakkur, Bangalore 560064, India"},{"name":"Department of Biochemistry, Indian Institute of Science 2 \u00a0 2 \u00a0 \u00a0 Bangalore 560012, India"}]}],"member":"286","published-online":{"date-parts":[[2006,10,4]]},"reference":[{"key":"2023012409224088300_b1","doi-asserted-by":"crossref","first-page":"18864","DOI":"10.1074\/jbc.M002810200","article-title":"Functional delineation of three groups of the ATP-dependent family of chromatin remodeling enzymes","volume":"275","author":"Boyer","year":"2000","journal-title":"J. Biol. Chem."},{"key":"2023012409224088300_b2","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S1097-2765(00)80430-X","article-title":"The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo","volume":"5","author":"Deuring","year":"2000","journal-title":"Mol. Cell"},{"key":"2023012409224088300_b3","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/nsmb0905-732","article-title":"Nucleosome remodelers on track","volume":"12","author":"Becker","year":"2005","journal-title":"Nat. Struct. Mol. Biol."},{"key":"2023012409224088300_b4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/embo-reports\/kvf075","article-title":"Chromatin remodeling enzymes: taming the machines","volume":"3","author":"Peterson","year":"2002","journal-title":"EMBO Rep."},{"key":"2023012409224088300_b5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0959-437X(00)00068-X","article-title":"Promoter targeting and chromatin remodeling by the SWI\/SNF complex","volume":"10","author":"Peterson","year":"2000","journal-title":"Curr. Opin. Genet. Dev."},{"key":"2023012409224088300_b6","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nrc1273","article-title":"The SWI\/SNF complex--chromatin and cancer","volume":"4","author":"Roberts","year":"2004","journal-title":"Nat. Rev. Cancer"},{"key":"2023012409224088300_b7","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/nsmb973","article-title":"Chromatin remodeling through directional DNA translocation from an internal nucleosomal site","volume":"12","author":"Saha","year":"2005","journal-title":"Nat. Struct. Mol. Biol."},{"key":"2023012409224088300_b8","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1128\/MCB.20.6.1899-1910.2000","article-title":"ATP-dependent chromatin-remodeling complexes","volume":"20","author":"Vignali","year":"2000","journal-title":"Mol. Cell. Biol."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/22\/23\/2940\/48842768\/bioinformatics_22_23_2940.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/22\/23\/2940\/48842768\/bioinformatics_22_23_2940.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T10:05:22Z","timestamp":1674554722000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/22\/23\/2940\/279566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,4]]},"references-count":8,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2006,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btl509","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2006,12,1]]},"published":{"date-parts":[[2006,10,4]]}}}