{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T13:47:34Z","timestamp":1768312054601,"version":"3.49.0"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Summary: Primary immunodeficiencies (PIDs) belong to the group of rare diseases. The European Society for Immunodeficiencies (ESID), is establishing an innovative European patient and research database network for continuous long-term documentation of patients, in order to improve the diagnosis, classification, prognosis and therapy of PIDs. The ESID Online Database is a web-based system aimed at data storage, data entry, reporting and the import of pre-existing data sources in an enterprise business-to-business integration (B2B). The online database is based on Java 2 Enterprise System (J2EE) with high-standard security features, which comply with data protection laws and the demands of a modern research platform.<\/jats:p><jats:p>Availability: The ESID Online Database is accessible via the official website (http:\/\/www.esid.org\/).<\/jats:p><jats:p>Contact: \u00a0b.grimbacher@medsch.ucl.ac.uk<\/jats:p><jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btl675","type":"journal-article","created":{"date-parts":[[2007,1,20]],"date-time":"2007-01-20T01:12:50Z","timestamp":1169255570000},"page":"654-655","source":"Crossref","is-referenced-by-count":42,"title":["The ESID Online Database network"],"prefix":"10.1093","volume":"23","author":[{"given":"D.","family":"Guzman","sequence":"first","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"},{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Veit","sequence":"additional","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Knerr","sequence":"additional","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Kindle","sequence":"additional","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Gathmann","sequence":"additional","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Eades-Perner","sequence":"additional","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Grimbacher","sequence":"additional","affiliation":[{"name":"1 Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Germany and 2Department of Clinical Immunology and Molecular Pathology, Royal Free Hospital, University College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2007,1,19]]},"reference":[{"key":"2023041109374834600_","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1172\/JCI26956","article-title":"Variable phenotypic expression of mutations in genes of the immune system","volume":"115","author":"Buckley","year":"2005","journal-title":"J. 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