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A client\u2013server mode, which is a novel feature for dotplot creation software, allows the user to calculate dotplots and color them by functional annotation without any prior downloading of sequence or annotation data.<\/jats:p><jats:p>Availability: Both source codes and executable binaries are available at http:\/\/mips.gsf.de\/services\/analysis\/gepard<\/jats:p><jats:p>Contact: \u00a0krumsiek@in.tum.de<\/jats:p>","DOI":"10.1093\/bioinformatics\/btm039","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T01:06:27Z","timestamp":1171933587000},"page":"1026-1028","source":"Crossref","is-referenced-by-count":662,"title":["Gepard: a rapid and sensitive tool for creating dotplots on genome scale"],"prefix":"10.1093","volume":"23","author":[{"given":"Jan","family":"Krumsiek","sequence":"first","affiliation":[{"name":"1 Institute for Bioinformatics (MIPS), GSF National Research Center for Environment and Health, Ingolst\u00e4dter Landstra\u00dfe 1, 85764 Neuherberg and 2Technische Universit\u00e4t M\u00fcnchen, Department of Genome Oriented Bioinformatics, Am Forum 1, 85354 Freising, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Arnold","sequence":"additional","affiliation":[{"name":"1 Institute for Bioinformatics (MIPS), GSF National Research Center for Environment and Health, Ingolst\u00e4dter Landstra\u00dfe 1, 85764 Neuherberg and 2Technische Universit\u00e4t M\u00fcnchen, Department of Genome Oriented Bioinformatics, Am Forum 1, 85354 Freising, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Rattei","sequence":"additional","affiliation":[{"name":"1 Institute for Bioinformatics (MIPS), GSF National Research Center for Environment and Health, Ingolst\u00e4dter Landstra\u00dfe 1, 85764 Neuherberg and 2Technische Universit\u00e4t M\u00fcnchen, Department of Genome Oriented Bioinformatics, Am Forum 1, 85354 Freising, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,2,19]]},"reference":[{"key":"2023041107550066900_","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S1570-8667(03)00065-0","article-title":"Replacing suffix trees with enhanced suffix arrays","volume":"2","author":"Abouelhoda","year":"2004","journal-title":"Journal of Discrete Algorithms"},{"key":"2023041107550066900_","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF00520346","article-title":"Locating gaps in amino acid sequences to optimize the homology between two proteins","volume":"3","author":"Fitch","year":"1969","journal-title":"Biochem. 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