{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:02:52Z","timestamp":1758394972857},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Gene Set Analyzer (GAzer) is a web-based integrated gene set analysis tool covering previously reported parametric and non-parametric models. Based on a simulation test for the reported algorithms, we classified and implemented three main statistical methods consisting of the z-statistic, gene permutation and sample permutation for ten gene set categories including Gene Ontology (GO) for human, mouse, rat and yeast. This tool identifies significantly altered gene sets scored by z-statistics and P-values from the z-test or permutation test and provides q-values and Bonferroni P-values to correct multiple hypothesis testing. GAzer allows users to observe changes in expression of each gene in a gene set or to see the significance of the gene sets containing a gene(s) of interest, thus allowing interactive data analysis both at the gene and gene set level. Moreover, GAzer offers extensive annotation for each gene.<\/jats:p>\n               <jats:p>Availability: The GAzer gene set analyzer is freely available at http:\/\/integromics.kobic.re.kr\/GAzer\/<\/jats:p>\n               <jats:p>Contact: kimsy@kribb.re.kr and chu@kribb.re.kr<\/jats:p>\n               <jats:p>Supplementary information: This can be found on the web page (http:\/\/integromics.kobic.re.kr\/GAzer\/supplement.jsp)<\/jats:p>","DOI":"10.1093\/bioinformatics\/btm144","type":"journal-article","created":{"date-parts":[[2007,4,28]],"date-time":"2007-04-28T00:14:37Z","timestamp":1177719277000},"page":"1697-1699","source":"Crossref","is-referenced-by-count":37,"title":["GAzer: gene set analyzer"],"prefix":"10.1093","volume":"23","author":[{"given":"Sang-Bae","family":"Kim","sequence":"first","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sungjin","family":"Yang","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seon-Kyu","family":"Kim","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Cheol","family":"Kim","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Goo","family":"Woo","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Volsky","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seon-Young","family":"Kim","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In-Sun","family":"Chu","sequence":"additional","affiliation":[{"name":"1 Korean BioInformation Center, KRIBB, Daejeon 305-806, 2Department of Applied Statistics, Yonsei University, Seoul, 120-749, Korea, 3Molecular Virology Division, St. Luke's-Roosevelt Hospital Center, 432 West 58th Street, Antenucci Building, Room 709, New York, NY 10019, USA and 4Human Genomics Laboratory, Genome Research Center, KRIBB, Daejeon 305-806, 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