{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:39:01Z","timestamp":1784129941716,"version":"3.55.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map quantitative trait loci (QTL) with individual effects, epistasis and QTL\u2013environment interaction. Currently, it is able to handle data from F2, backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F2 and BCnFn populations). The Windows version of QTLNetwork was developed with a graphical user interface. Alternatively, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/ibi.zju.edu.cn\/software\/qtlnetwork<\/jats:p>\n               <jats:p>Contact: \u00a0jzhu@zju.edu.cn<\/jats:p>","DOI":"10.1093\/bioinformatics\/btm494","type":"journal-article","created":{"date-parts":[[2008,1,18]],"date-time":"2008-01-18T01:14:37Z","timestamp":1200618877000},"page":"721-723","source":"Crossref","is-referenced-by-count":365,"title":["QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations"],"prefix":"10.1093","volume":"24","author":[{"given":"Jian","family":"Yang","sequence":"first","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengcheng","family":"Hu","sequence":"additional","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Hu","sequence":"additional","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongdong","family":"Yu","sequence":"additional","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Xia","sequence":"additional","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuzi","family":"Ye","sequence":"additional","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhu","sequence":"additional","affiliation":[{"name":"1 Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,1,17]]},"reference":[{"key":"2023020210120962700_B1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/bioinformatics\/btg112","article-title":"R\/qtl: QTL mapping in experimental crosses","volume":"19","author":"Broman","year":"2003","journal-title":"Bioinformatics"},{"key":"2023020210120962700_B2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/genetics\/142.1.285","article-title":"Permutation tests for multiple loci affecting a quantitative character","volume":"142","author":"Doerge","year":"1996","journal-title":"Genetics"},{"key":"2023020210120962700_B3","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/hdy.1992.131","article-title":"A simple regression method for mapping quantitative traits in line crosses using flanking markers","volume":"69","author":"Haley","year":"1992","journal-title":"Heredity"},{"key":"2023020210120962700_B4","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1093\/genetics\/152.3.1203","article-title":"Multiple interval mapping for quantitative trait loci","volume":"152","author":"Kao","year":"1999","journal-title":"Genetics"},{"key":"2023020210120962700_B5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/genetics\/121.1.185","article-title":"Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps","volume":"121","author":"Lander","year":"1989","journal-title":"Genetics"},{"key":"2023020210120962700_B6","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/0888-7543(87)90010-3","article-title":"MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations","volume":"1","author":"Lander","year":"1987","journal-title":"Genomics"},{"key":"2023020210120962700_B7","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1007\/s00335-001-1016-3","article-title":"Map Manager QTX, cross-platform software for genetic mapping","volume":"12","author":"Manly","year":"2001","journal-title":"Mamm. 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