{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,19]],"date-time":"2023-02-19T23:28:08Z","timestamp":1676849288647},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":3236,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/uk\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Bioinformatics involves the collection, organization and analysis of large amounts of biological data, using networks of computers and databases. Developing countries in the Asia-Pacific region are just moving into this new field of information-based biotechnology. However, the computational infrastructure and network bandwidths available in these countries are still at a basic level compared to that in developed countries. In this study, we assessed the utility of a BitTorrent-based Peer-to-Peer (btP2P) file distribution model for automatic synchronization and distribution of large amounts of biological data among developing countries. The initial country-level nodes in the Asia-Pacific region comprised Thailand, Korea and Singapore. The results showed a significant improvement in download performance using btP2P\u2014three times faster overall download performance than conventional File Transfer Protocol (FTP). This study demonstrated the reliability of btP2P in the dissemination of continuously growing multi-gigabyte biological databases across the three Asia-Pacific countries. The download performance for btP2P can be further improved by including more nodes from other countries into the network. This suggests that the btP2P technology is appropriate for automatic synchronization and distribution of biological databases and software over low-bandwidth networks among developing countries in the Asia-Pacific region.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/everest.bic.nus.edu.sg\/p2p\/<\/jats:p>\n               <jats:p>Contact: \u00a0usangket@yahoo.com<\/jats:p>","DOI":"10.1093\/bioinformatics\/btm570","type":"journal-article","created":{"date-parts":[[2007,11,24]],"date-time":"2007-11-24T01:13:32Z","timestamp":1195866812000},"page":"299-301","source":"Crossref","is-referenced-by-count":4,"title":["Automatic synchronization and distribution of biological databases and software over low-bandwidth networks among developing countries"],"prefix":"10.1093","volume":"24","author":[{"given":"Unitsa","family":"Sangket","sequence":"first","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Amornrat","family":"Phongdara","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Wilaiwan","family":"Chotigeat","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Darran","family":"Nathan","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Woo-Yeon","family":"Kim","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Jong","family":"Bhak","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Chumpol","family":"Ngamphiw","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Sissades","family":"Tongsima","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Asif M.","family":"Khan","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Honghuang","family":"Lin","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]},{"given":"Tin Wee","family":"Tan","sequence":"additional","affiliation":[{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"},{"name":"1 Center for Genomics and Bioinformatics Research, Prince of Songkla University, Thailand, 2Asia-Pacific Bioinformatics Network, 3Korean BioInformation Center (KOBIC), KRIBB, Korea, 4Biostatistics and Informatics Laboratory, Genome Institute, National Center for Genetic Engineering and Biotechnology, Thailand and 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}]}],"member":"286","published-online":{"date-parts":[[2007,11,23]]},"reference":[{"key":"2023020209490470700_B1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1145\/1273445.1273449","article-title":"Can ISPs and P2P users cooperate for improved performance?","volume":"37","author":"Aggarwal","year":"2007","journal-title":"ACM SIGCOMM Comput. Commun. Rev."},{"key":"2023020209490470700_B2","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1093\/bioinformatics\/bth219","article-title":"Bio-Mirror project for public bio-data distribution","volume":"20","author":"Gilbert","year":"2004","journal-title":"Bioinformatics"},{"key":"2023020209490470700_B3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1109\/JSAC.2007.070116","article-title":"A Performance Study of BitTorrent-like Peer-to-Peer Systems","volume":"25","author":"Guo","year":"2007","journal-title":"IEEE J. Selected Areas Commun."},{"key":"2023020209490470700_B4","first-page":"1","article-title":"Computational Sociology for Systems \u201cIn the Wild\u201d: The Case of BitTorrent","volume":"6","author":"Hales","year":"2005","journal-title":"IEEE Distrib. Syst."},{"key":"2023020209490470700_B5","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/bmb.2003.494031010160","article-title":"The S-Star trial bioinformatics course \u2013 an on-line learning success","volume":"31","author":"Lim","year":"2003","journal-title":"Biochem. Mol. Biol. Educ."},{"key":"2023020209490470700_B6","first-page":"101","article-title":"APBioNet: the Asia Pacific regional consortium for bioinformatics","volume":"1","author":"Ranganathan","year":"2002","journal-title":"Appl. Bioinformatics"},{"issue":"Suppl. 5","key":"2023020209490470700_B7","article-title":"Establishing bioinformatics research in the Asia Pacific","volume":"7","author":"Ranganathan","year":"2006","journal-title":"BMC Bioinformatics"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/24\/2\/299\/49044832\/bioinformatics_24_2_299.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/24\/2\/299\/49044832\/bioinformatics_24_2_299.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T10:29:09Z","timestamp":1675333749000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/24\/2\/299\/228032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,23]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,1,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btm570","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2008,1,15]]},"published":{"date-parts":[[2007,11,23]]}}}