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We present a technique for characterizing the modal frequencies of oscillation using continuous wavelet decomposition to non-parametrically model changes in amplitude and period while removing baseline effects and noise.<\/jats:p>\n               <jats:p>Availability: The method has been implemented as the package waveclock for the free statistical software program R and is available for download from http:\/\/cran.r-project.org\/<\/jats:p>\n               <jats:p>Contact: \u00a0thomas.price@iop.kcl.ac.uk<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary figures are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btn521","type":"journal-article","created":{"date-parts":[[2008,10,19]],"date-time":"2008-10-19T00:13:35Z","timestamp":1224375215000},"page":"2794-2795","source":"Crossref","is-referenced-by-count":41,"title":["WAVECLOCK: wavelet analysis of circadian oscillation"],"prefix":"10.1093","volume":"24","author":[{"given":"Tom S.","family":"Price","sequence":"first","affiliation":[{"name":"1 Institute of Psychiatry, Kings College London, 2Institute for Translational Medicine and Therapeutics, University of Pennsylvania and 3Bio Directorate, Science Foundation Ireland (SFI)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie E.","family":"Baggs","sequence":"additional","affiliation":[{"name":"1 Institute of Psychiatry, Kings College London, 2Institute for Translational Medicine and Therapeutics, University of Pennsylvania and 3Bio Directorate, Science Foundation Ireland (SFI)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne M.","family":"Curtis","sequence":"additional","affiliation":[{"name":"1 Institute of Psychiatry, Kings College London, 2Institute for Translational Medicine and Therapeutics, University of Pennsylvania and 3Bio Directorate, Science Foundation Ireland (SFI)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garret A.","family":"FitzGerald","sequence":"additional","affiliation":[{"name":"1 Institute of Psychiatry, Kings College London, 2Institute for Translational Medicine and Therapeutics, University of Pennsylvania and 3Bio Directorate, Science Foundation Ireland (SFI)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Hogenesch","sequence":"additional","affiliation":[{"name":"1 Institute of Psychiatry, Kings College London, 2Institute for Translational Medicine and Therapeutics, University of Pennsylvania and 3Bio Directorate, Science Foundation Ireland (SFI)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2008,10,17]]},"reference":[{"key":"2023020212240086300_B1","volume-title":"Practical Time-Frequency Analysis: Gabor and Wavelet Transforms with an Implementation in S.","author":"Carmona","year":"1998"},{"key":"2023020212240086300_B2","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1073\/pnas.0611680104","article-title":"Circadian variation of blood pressure and the vascular response to asynchronous stress","volume":"104","author":"Curtis","year":"2007","journal-title":"Proc. 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