{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T08:23:39Z","timestamp":1769329419048,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":2870,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/uk\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: Two methods are commonly used to report on evidence carried by forensic DNA profiles: the \u2018Random Man Not Excluded\u2019 (RMNE) approach and the likelihood ratio (LR) approach. It is often claimed a major advantage of the LR method that dropout can be assessed probabilistically.<\/jats:p>\n               <jats:p>Results: In this article, a new RMNE measure is proposed that like-wise accounts for allelic dropout in an observed forensic DNA profile. We discuss the necessary calculations, underline their simplicity and provide a tool for performing the calculations.<\/jats:p>\n               <jats:p>Availability: An Excel file with preprogrammed calculations of RMNE probabilities for DNA profiles up to 16 loci and with a maximum of two dropouts is available at: http:\/\/www.labfbt.UGent.be\/RMNE.php<\/jats:p>\n               <jats:p>Contact: \u00a0dieter.deforce@ugent.be<\/jats:p>","DOI":"10.1093\/bioinformatics\/btn608","type":"journal-article","created":{"date-parts":[[2008,11,25]],"date-time":"2008-11-25T01:13:06Z","timestamp":1227575586000},"page":"225-229","source":"Crossref","is-referenced-by-count":23,"title":["Impact of allelic dropout on evidential value of forensic DNA profiles using RMNE"],"prefix":"10.1093","volume":"25","author":[{"given":"F.","family":"Van Nieuwerburgh","sequence":"first","affiliation":[{"name":"1 Laboratory for Pharmaceutical Biotechnology, Ghent University, Harelbekestraat 72, B-9000 Ghent and 2Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281, S9, B-9000 Ghent, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Goetghebeur","sequence":"additional","affiliation":[{"name":"1 Laboratory for Pharmaceutical Biotechnology, Ghent University, Harelbekestraat 72, B-9000 Ghent and 2Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281, S9, B-9000 Ghent, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Vandewoestyne","sequence":"additional","affiliation":[{"name":"1 Laboratory for Pharmaceutical Biotechnology, Ghent University, Harelbekestraat 72, B-9000 Ghent and 2Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281, S9, B-9000 Ghent, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Deforce","sequence":"additional","affiliation":[{"name":"1 Laboratory for Pharmaceutical Biotechnology, Ghent University, Harelbekestraat 72, B-9000 Ghent and 2Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281, S9, B-9000 Ghent, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2008,11,23]]},"reference":[{"key":"2023013109592367700_B1","first-page":"27","article-title":"A framework for interpreting evidence.","volume-title":"Forensic DNA Evidence Interpretation.","author":"Buckleton","year":"2005"},{"key":"2023013109592367700_B2","first-page":"218","article-title":"Mixtures.","volume-title":"Forensic DNA Evidence Interpretation.","author":"Buckleton","year":"2005"},{"key":"2023013109592367700_B3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.forsciint.2004.04.077","article-title":"Interpretation of repeat measurement DNA evidence allowing for multiple contributors and population substructure","volume":"148","author":"Curran","year":"2005","journal-title":"Forensic Sci. Int."},{"key":"2023013109592367700_B4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0015-7368(91)73116-2","article-title":"A guide to interpreting single locus profiles of DNA mixtures in forensic cases","volume":"31","author":"Evett","year":"1991","journal-title":"J. Forensic Sci. Soc"},{"key":"2023013109592367700_B5","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.forsciint.2006.04.009","article-title":"DNA commission of the International Society of Forensic Genetics: Recommendations on the interpretation of mixtures","volume":"160","author":"Gill","year":"2006","journal-title":"Forensic Sci. Int."},{"key":"2023013109592367700_B6","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0379-0738(00)00158-4","article-title":"An investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA","volume":"112","author":"Gill","year":"2000","journal-title":"Forensic Sci. Int."},{"key":"2023013109592367700_B7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.fsigen.2007.06.007","article-title":"Interpretation of DNA mixtures\u2013European consensus on principles","volume":"1","author":"Morling","year":"2007","journal-title":"Forensic Sci. Int.: Genet"},{"key":"2023013109592367700_B8","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1355-0306(98)72101-X","article-title":"Probabilistic reasoning in the law\u2013Part 1: assessment of probabilities and explanation of the value of DNA evidence.","volume":"38","author":"Taroni","year":"1998","journal-title":"Sci. Justice"},{"key":"2023013109592367700_B9","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1520\/JFS14100J","article-title":"Interpreting DNA mixtures","volume":"42","author":"Weir","year":"1997","journal-title":"J. Forensic Sci."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/25\/2\/225\/48982033\/bioinformatics_25_2_225.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/25\/2\/225\/48982033\/bioinformatics_25_2_225.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T18:36:19Z","timestamp":1675190179000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/25\/2\/225\/219671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,23]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,1,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btn608","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2009,1,15]]},"published":{"date-parts":[[2008,11,23]]}}}