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Its originality lies in the fact that it searches for a latent modular structure to drive the inference procedure through adaptive penalization of the concentration matrix.<\/jats:p><jats:p>Availability: Under the GNU General Public Licence at http:\/\/cran.r-project.org\/web\/packages\/simone\/<\/jats:p><jats:p>Contact: \u00a0julien.chiquet@genopole.cnrs.fr<\/jats:p>","DOI":"10.1093\/bioinformatics\/btn637","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T01:13:35Z","timestamp":1228958015000},"page":"417-418","source":"Crossref","is-referenced-by-count":32,"title":["SIMoNe: Statistical Inference for MOdular NEtworks"],"prefix":"10.1093","volume":"25","author":[{"given":"Julien","family":"Chiquet","sequence":"first","affiliation":[{"name":"UMR CNRS 8071 Statistique et G\u00e9nome, 523, place des Terrasses, F-91000 \u00c9vry, France"}]},{"given":"Alexander","family":"Smith","sequence":"additional","affiliation":[{"name":"UMR CNRS 8071 Statistique et G\u00e9nome, 523, place des Terrasses, F-91000 \u00c9vry, France"}]},{"given":"Gilles","family":"Grasseau","sequence":"additional","affiliation":[{"name":"UMR CNRS 8071 Statistique et G\u00e9nome, 523, place des Terrasses, F-91000 \u00c9vry, France"}]},{"given":"Catherine","family":"Matias","sequence":"additional","affiliation":[{"name":"UMR CNRS 8071 Statistique et G\u00e9nome, 523, place des Terrasses, F-91000 \u00c9vry, France"}]},{"given":"Christophe","family":"Ambroise","sequence":"additional","affiliation":[{"name":"UMR CNRS 8071 Statistique et G\u00e9nome, 523, place des Terrasses, F-91000 \u00c9vry, France"}]}],"member":"286","published-online":{"date-parts":[[2008,12,10]]},"reference":[{"key":"2023013110014035100_B1","doi-asserted-by":"crossref","article-title":"Inferring Gaussian graphical models with latent structure.","author":"Ambroise","DOI":"10.1214\/08-EJS314"},{"key":"2023013110014035100_B2","first-page":"485","article-title":"Model selection through sparse maximum likelihood estimation for multivariate {G}aussian or binary data.","volume":"9","author":"Banerjee","year":"2008","journal-title":"J. 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