{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T11:21:23Z","timestamp":1742383283135},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":2825,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/uk\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Many genomic and proteomic analyses generate as a result a tree of genes or proteins. These trees are often large (containing tens of thousands of nodes and edges), and need a visualization tool to fully display all the information contained in the tree. Clustering analysis can be performed on these trees to obtain clusters of proteins, and we need an efficient way to visualize the clustering results. We present a novel tree visualization tool to help with such analyses.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/www2.renci.org\/~jeff\/software\/bin\/win32\/ProteinVis-2.1.6-win32.zip<\/jats:p>\n               <jats:p>Contact: \u00a0jeff@renci.org; xguan@renci.org<\/jats:p>","DOI":"10.1093\/bioinformatics\/btn656","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T01:24:23Z","timestamp":1231377863000},"page":"557-558","source":"Crossref","is-referenced-by-count":6,"title":["A novel method for large tree visualization"],"prefix":"10.1093","volume":"25","author":[{"given":"Jeff","family":"Heard","sequence":"first","affiliation":[{"name":"1 Renaissance Computing Institute, 100 Europa Drive, Chapel Hill, NC 27519 and 2Department of Pathology and Laboratory of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA"}]},{"given":"William","family":"Kaufmann","sequence":"additional","affiliation":[{"name":"1 Renaissance Computing Institute, 100 Europa Drive, Chapel Hill, NC 27519 and 2Department of Pathology and Laboratory of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA"}]},{"given":"Xiaojun","family":"Guan","sequence":"additional","affiliation":[{"name":"1 Renaissance Computing Institute, 100 Europa Drive, Chapel Hill, NC 27519 and 2Department of Pathology and Laboratory of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA"}]}],"member":"286","published-online":{"date-parts":[[2009,1,7]]},"reference":[{"key":"2023013110095359600_B1"},{"key":"2023013110095359600_B2","first-page":"253","volume-title":"Introduction to Algorithms.","author":"Cormen","year":"2001","edition":"2nd edn"},{"key":"2023013110095359600_B3"},{"key":"2023013110095359600_B4","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1186\/1471-2105-8-460","article-title":"Dendroscope: an interactive viewer for large phylogenetic trees","volume":"8","author":"Huson","year":"2007","journal-title":"BMC Bioinformatics"},{"key":"2023013110095359600_B5","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1093\/bioinformatics\/btn235","article-title":"PhyloWidget: webbased visualizations for the tree of life","volume":"24","author":"Jordan","year":"2008","journal-title":"Bioinformatics"},{"key":"2023013110095359600_B6","first-page":"920","article-title":"A space efficient clustered visualization of large graphs","volume-title":"Fourth International Conference on Image and Graphics (ICIG 2007) 2007.","author":"Nguyen","year":"2007"},{"key":"2023013110095359600_B7","doi-asserted-by":"crossref","first-page":"3246","DOI":"10.1093\/bioinformatics\/bth349","article-title":"Java Treeview\u2014extensible visualization of microarray data","volume":"17","author":"Saldanha","year":"2004","journal-title":"Bioinformatics"},{"key":"2023013110095359600_B8","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1093\/bioinformatics\/btk052","article-title":"A interactive power analysis tool for microarray hypothesis testing and generation","volume":"7","author":"Seo","year":"2006","journal-title":"Bioinformatics"},{"key":"2023013110095359600_B9","first-page":"28","article-title":"Treemap, Radial Tree and 3D Tree Visualizations","volume-title":"IEEE Information Visualization Conference.","author":"Sheth","year":"2003"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/25\/4\/557\/48982940\/bioinformatics_25_4_557.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/25\/4\/557\/48982940\/bioinformatics_25_4_557.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T18:26:58Z","timestamp":1675189618000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/25\/4\/557\/249801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,7]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,2,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btn656","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2009,2,15]]},"published":{"date-parts":[[2009,1,7]]}}}