{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T08:25:09Z","timestamp":1769415909720,"version":"3.49.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: FlexServ is a web-based tool for the analysis of protein flexibility. The server incorporates powerful protocols for the coarse-grained determination of protein dynamics using different versions of Normal Mode Analysis (NMA), Brownian dynamics (BD) and Discrete Dynamics (DMD). It can also analyze user provided trajectories. The server allows a complete analysis of flexibility using a large variety of metrics, including basic geometrical analysis, B-factors, essential dynamics, stiffness analysis, collectivity measures, Lindemann's indexes, residue correlation, chain-correlations, dynamic domain determination, hinge point detections, etc. Data is presented through a web interface as plain text, 2D and 3D graphics.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/mmb.pcb.ub.es\/FlexServ; http:\/\/www.inab.org<\/jats:p>\n               <jats:p>Contact: \u00a0modesto@mmb.pcb.ub.es or gelpi@mmb.pcb.ub.es<\/jats:p>\n               <jats:p>Supplementary information: Additional information and methodology details can be found at http:\/\/mmb.pcb.ub.es\/FlexServ\/help.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btp304","type":"journal-article","created":{"date-parts":[[2009,5,9]],"date-time":"2009-05-09T00:15:02Z","timestamp":1241828102000},"page":"1709-1710","source":"Crossref","is-referenced-by-count":75,"title":["FlexServ: an integrated tool for the analysis of protein flexibility"],"prefix":"10.1093","volume":"25","author":[{"given":"Jordi","family":"Camps","sequence":"first","affiliation":[{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"},{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"}]},{"given":"Oliver","family":"Carrillo","sequence":"additional","affiliation":[{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"}]},{"given":"Agust\u00ed","family":"Emperador","sequence":"additional","affiliation":[{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"}]},{"given":"Laura","family":"Orellana","sequence":"additional","affiliation":[{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"}]},{"given":"Adam","family":"Hospital","sequence":"additional","affiliation":[{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"},{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep 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4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"}]},{"given":"Marco","family":"D'Abramo","sequence":"additional","affiliation":[{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 08034, Spain, 3National Institute of Bioinformatics, Structural Bioinformatics, Josep Samitier 1-5 and 4Department of Biochemistry and Molecular Biology, University of Barcelona, Av Diagonal 645, Barcelona 08028, Spain"},{"name":"1 Joint IRB-BSC Program on Computational Biology, Institute of Research in Biomedicine, Barcelona Science Park, Josep Samitier 1-5, Barcelona 08028 and Barcelona Supercomputing Centre, 2National Institute of Bioinformatics, Computational Bioinformatics, Jordi Girona 31, Barcelona 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