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We find that given a fixed coverage, longer reads (implying fewer of them) are preferable.<\/jats:p>\n               <jats:p>Availability: The executable and user manual can be freely downloaded from ftp:\/\/ftp.sanger.ac.uk\/pub\/zn1\/HI.<\/jats:p>\n               <jats:p>Contact: \u00a0ql2@sanger.ac.uk<\/jats:p>","DOI":"10.1093\/bioinformatics\/btp412","type":"journal-article","created":{"date-parts":[[2009,7,2]],"date-time":"2009-07-02T00:40:46Z","timestamp":1246495246000},"page":"2436-2437","source":"Crossref","is-referenced-by-count":12,"title":["HI: haplotype improver using paired-end short reads"],"prefix":"10.1093","volume":"25","author":[{"given":"Quan","family":"Long","sequence":"first","affiliation":[{"name":"The Wellcome Trust Sanger Institute, Hinxton, Cambs, CB10 1SA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"MacArthur","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Sanger Institute, Hinxton, Cambs, CB10 1SA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zemin","family":"Ning","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Sanger Institute, Hinxton, Cambs, CB10 1SA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Tyler-Smith","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Sanger Institute, Hinxton, Cambs, CB10 1SA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2009,7,1]]},"reference":[{"key":"2023013112121654300_B1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1093\/bioinformatics\/18.2.337","article-title":"Generating samples under a Wright-Fisher neutral model of genetic variation","volume":"18","author":"Hudson","year":"2002","journal-title":"Bioinformatics"},{"key":"2023013112121654300_B2","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1101\/gr.5894107","article-title":"Diploid genome reconstruction of Ciona intestinalis and comparative analysis with Ciona savignyi","volume":"17","author":"Kim","year":"2007","journal-title":"Genome Res."},{"key":"2023013112121654300_B3","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1089\/1066527041410454","article-title":"Haplotype reconstruction from SNP alignment","volume":"11","author":"Li","year":"2004","journal-title":"J. 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