{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:26:44Z","timestamp":1768278404066,"version":"3.49.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: \u00a0Intervor is a software computing a parameter-free representation of macro\u2013molecular interfaces, based on the \u03b1-complex of the atoms. Given two interacting partners, possibly with water molecules squeezed in-between them, Intervor computes an interface model which has the following characteristics: (i) it identifies the atoms of the partners which are in direct contact and those whose interaction is water mediated, (ii) it defines a geometric complex separating the partners, the Voronoi interface, whose geometric and topological descriptions are straightforward (surface area, number of patches, curvature), (iii) it allows the definition of the depth of atoms at the interface, thus going beyond the traditional dissection of an interface into a core and a rim. These features can be used to investigate correlations between structural parameters and key properties such as the conservation of residues, their polarity, the water dynamics at the interface, mutagenesis data, etc.<\/jats:p>\n               <jats:p>Availability: \u00a0Intervor can be run from the web site http:\/\/cgal.inria.fr\/abs\/Intervor or upon downloading the binary file. Plugins are also made available for VMD and Pymol.<\/jats:p>\n               <jats:p>Contact: \u00a0frederic.cazals@sophia.inria.fr<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq052","type":"journal-article","created":{"date-parts":[[2010,2,8]],"date-time":"2010-02-08T01:12:44Z","timestamp":1265591564000},"page":"964-965","source":"Crossref","is-referenced-by-count":21,"title":["Modeling macro\u2013molecular interfaces with <tt>Intervor<\/tt>"],"prefix":"10.1093","volume":"26","author":[{"given":"S\u00e9bastien","family":"Loriot","sequence":"first","affiliation":[{"name":"INRIA Sophia-Antipolis-M\u00e9diterran\u00e9e, Algorithms-Biology-Structure, Sophia-Antipolis, France"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Cazals","sequence":"additional","affiliation":[{"name":"INRIA Sophia-Antipolis-M\u00e9diterran\u00e9e, Algorithms-Biology-Structure, Sophia-Antipolis, France"}]}],"member":"286","published-online":{"date-parts":[[2010,2,7]]},"reference":[{"key":"2023012508034844400_B1","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.jmb.2003.12.073","article-title":"A dissection of specific and non-specific protein\u2013protein interfaces","volume":"336","author":"Bahadur","year":"2004","journal-title":"J. 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