{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T16:31:43Z","timestamp":1682267503998},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":2417,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/uk\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Many large \u2018omics\u2019 datasets have been published and many more are expected in the near future. New analysis methods are needed for best exploitation. We have developed a graphical user interface (GUI) for easy data analysis. Our discovery of all significant substructures (DASS) approach elucidates the underlying modularity, a typical feature of complex biological data. It is related to biclustering and other data mining approaches. Importantly, DASS-GUI also allows handling of multi-sets and calculation of statistical significances. DASS-GUI contains tools for further analysis of the identified patterns: analysis of the pattern hierarchy, enrichment analysis, module validation, analysis of additional numerical data, easy handling of synonymous names, clustering, filtering and merging. Different export options allow easy usage of additional tools such as Cytoscape.<\/jats:p>\n               <jats:p>Availability: Source code, pre-compiled binaries for different systems, a comprehensive tutorial, case studies and many additional datasets are freely available at http:\/\/www.ifr.ac.uk\/dass\/gui\/. DASS-GUI is implemented in Qt.<\/jats:p>\n               <jats:p>Contact: \u00a0jehol@psb.vib-ugent.be; thomas.wilhelm@bbsrc.ac.uk<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq071","type":"journal-article","created":{"date-parts":[[2010,2,20]],"date-time":"2010-02-20T01:49:44Z","timestamp":1266630584000},"page":"987-989","source":"Crossref","is-referenced-by-count":3,"title":["DASS-GUI: a user interface for identification and analysis of significant patterns in non-sequential data"],"prefix":"10.1093","volume":"26","author":[{"given":"Jens","family":"Hollunder","sequence":"first","affiliation":[{"name":"1 Department of Plant Systems Biology, VIB, 2 Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium, 3 Biocomputing Group, Leibniz Institute for Age Research \u2013 Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany and 4 Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK"},{"name":"1 Department of Plant Systems Biology, VIB, 2 Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium, 3 Biocomputing Group, Leibniz Institute for Age Research \u2013 Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany and 4 Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK"}]},{"given":"Maik","family":"Friedel","sequence":"additional","affiliation":[{"name":"1 Department of Plant Systems Biology, VIB, 2 Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium, 3 Biocomputing Group, Leibniz Institute for Age Research \u2013 Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany and 4 Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK"}]},{"given":"Martin","family":"Kuiper","sequence":"additional","affiliation":[{"name":"1 Department of Plant Systems Biology, VIB, 2 Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium, 3 Biocomputing Group, Leibniz Institute for Age Research \u2013 Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany and 4 Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK"},{"name":"1 Department of Plant Systems Biology, VIB, 2 Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium, 3 Biocomputing Group, Leibniz Institute for Age Research \u2013 Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany and 4 Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK"}]},{"given":"Thomas","family":"Wilhelm","sequence":"additional","affiliation":[{"name":"1 Department of Plant Systems Biology, VIB, 2 Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium, 3 Biocomputing Group, Leibniz Institute for Age Research \u2013 Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany and 4 Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK"}]}],"member":"286","published-online":{"date-parts":[[2010,2,19]]},"reference":[{"key":"2023012508033217000_B1","first-page":"487","article-title":"Fast algorithms for mining association rules","volume-title":"Proceedings of 20th International Conference on Very Large Data Bases","author":"Agrawal","year":"1994"},{"key":"2023012508033217000_B2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. 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