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Different topological characteristics, such as the centrality of nodes in the network or their tendency to form clusters, can be computed and compared with those of known cellular pathways and processes.<\/jats:p>\n               <jats:p>Availability: Freely available at http:\/\/www.infobiotics.net\/topogsa<\/jats:p>\n               <jats:p>Contact: \u00a0nxk@cs.nott.ac.uk; avalencia@cnio.es<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq131","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T02:48:28Z","timestamp":1269485308000},"page":"1271-1272","source":"Crossref","is-referenced-by-count":58,"title":["TopoGSA: network topological gene set analysis"],"prefix":"10.1093","volume":"26","author":[{"given":"Enrico","family":"Glaab","sequence":"first","affiliation":[{"name":"1 School of Computer Science, Nottingham University, Jubilee Campus, Nottingham, UK and 2 Structural Biology and Biocomputing Program, CNIO, Madrid, Spain"}]},{"given":"Ana\u00efs","family":"Baudot","sequence":"additional","affiliation":[{"name":"1 School of Computer Science, Nottingham University, Jubilee Campus, Nottingham, UK and 2 Structural Biology and Biocomputing Program, CNIO, Madrid, Spain"}]},{"given":"Natalio","family":"Krasnogor","sequence":"additional","affiliation":[{"name":"1 School of Computer Science, Nottingham University, Jubilee Campus, Nottingham, UK and 2 Structural Biology and Biocomputing Program, CNIO, Madrid, Spain"}]},{"given":"Alfonso","family":"Valencia","sequence":"additional","affiliation":[{"name":"1 School of Computer Science, Nottingham University, Jubilee Campus, Nottingham, UK and 2 Structural Biology and Biocomputing Program, CNIO, Madrid, Spain"}]}],"member":"286","published-online":{"date-parts":[[2010,3,24]]},"reference":[{"key":"2023012508172089300_B1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1186\/1471-2105-10-275","article-title":"Comparative study of gene set enrichment methods","volume":"10","author":"Abatangelo","year":"2009","journal-title":"BMC Bioinformatics"},{"key":"2023012508172089300_B2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/nar\/29.1.37","article-title":"The InterPro database, an integrated documentation resource for protein families, domains and functional sites","volume":"29","author":"Apweiler","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"2023012508172089300_B3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene Ontology: tool for the unification of biology","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat. 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