{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:47:40Z","timestamp":1761662860097},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>High-throughput sequencing (HTS) has opened up a new era for small RNA (sRNA) exploration. Using HTS data for a global survey of sRNAs in 26 angiosperms, elevated GC contents were detected in the monocots, whereas the 5\u2032-terminal compositions were quite uniform among the angiosperms. Chromosome-wide distribution patterns of sRNAs were investigated by using scrolling-window analysis. We performed de novo natural antisense transcript (NAT) prediction, and found that the overlapping regions of trans-NATs, but not cis-NATs, were hotspots for sRNA generation. One cis-NAT generates phased natural antisense short interfering RNAs (nat-siRNAs) specifically from flowers in Arabidopsis, while one in rice produces phased nat-siRNAs from grains, suggesting their organ-specific regulatory roles.<\/jats:p>\n               <jats:p>Contact: \u00a0clspwu@zju.edu.cn; mchen@zju.edu.cn<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq150","type":"journal-article","created":{"date-parts":[[2010,4,9]],"date-time":"2010-04-09T00:19:08Z","timestamp":1270772348000},"page":"1391-1394","source":"Crossref","is-referenced-by-count":22,"title":["Small RNAs in angiosperms: sequence characteristics, distribution and generation"],"prefix":"10.1093","volume":"26","author":[{"given":"Dijun","family":"Chen","sequence":"first","affiliation":[{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"},{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijun","family":"Meng","sequence":"additional","affiliation":[{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"},{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. 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Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"},{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Cao","sequence":"additional","affiliation":[{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibin","family":"Gu","sequence":"additional","affiliation":[{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Wu","sequence":"additional","affiliation":[{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"},{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Chen","sequence":"additional","affiliation":[{"name":"1 Department of Bioinformatics, 2 State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences and 3 James D. 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