{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:02:09Z","timestamp":1761919329535},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Genome-wide association studies (GWAS), which produce huge volumes of data, are now being carried out by many groups around the world, creating a need for user-friendly tools for data quality control (QC) and analysis. One critical aspect of GWAS QC is evaluating genotype cluster plots to verify sensible genotype calling in putatively associated single nucleotide polymorphisms (SNPs). Evoker is a tool for visualizing genotype cluster plots, and provides a solution to the computational and storage problems related to working with such large datasets.<\/jats:p>\n               <jats:p>Availability: \u00a0http:\/\/www.sanger.ac.uk\/resources\/software\/evoker\/<\/jats:p>\n               <jats:p>Contact: \u00a0barrett@sanger.ac.uk<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq280","type":"journal-article","created":{"date-parts":[[2010,5,28]],"date-time":"2010-05-28T00:46:57Z","timestamp":1275007617000},"page":"1786-1787","source":"Crossref","is-referenced-by-count":32,"title":["Evoker: a visualization tool for genotype intensity data"],"prefix":"10.1093","volume":"26","author":[{"given":"James A.","family":"Morris","sequence":"first","affiliation":[{"name":"1 Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH and 2 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK"}]},{"given":"Joshua C.","family":"Randall","sequence":"additional","affiliation":[{"name":"1 Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH and 2 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK"}]},{"given":"Julian B.","family":"Maller","sequence":"additional","affiliation":[{"name":"1 Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH and 2 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK"}]},{"given":"Jeffrey C.","family":"Barrett","sequence":"additional","affiliation":[{"name":"1 Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH and 2 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK"}]}],"member":"286","published-online":{"date-parts":[[2010,5,27]]},"reference":[{"key":"2023012507583282600_B1","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1038\/ng.483","article-title":"Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region","volume":"41","author":"UK IBD Genetics Consortium WTCCC2","year":"2009","journal-title":"Nat. Genet."},{"key":"2023012507583282600_B2","doi-asserted-by":"crossref","first-page":"R122","DOI":"10.1093\/hmg\/ddn288","article-title":"Practical aspects of imputation-driven meta-analysis of genome-wide association studies","volume":"17","author":"de Bakker","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"2023012507583282600_B3","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1056\/NEJMp0808934","article-title":"Genomewide association studies\u2013illuminating biologic pathways","volume":"360","author":"Hirschhorn","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"2023012507583282600_B4","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/ng.237","article-title":"Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs","volume":"40","author":"Korn","year":"2008","journal-title":"Nat. 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Genet."},{"key":"2023012507583282600_B6","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1093\/bioinformatics\/btm443","article-title":"A genotype calling algorithm for the Illumina BeadArray platform","volume":"23","author":"Teo","year":"2007","journal-title":"Bioinformatics"},{"key":"2023012507583282600_B7","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nature05911","article-title":"Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls","volume":"447","author":"Wellcome Trust Case Control Consortium","year":"2007","journal-title":"Nature"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/14\/1786\/48853018\/bioinformatics_26_14_1786.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/14\/1786\/48853018\/bioinformatics_26_14_1786.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T07:58:46Z","timestamp":1674633526000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/26\/14\/1786\/178674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,27]]},"references-count":7,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2010,7,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btq280","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2010,7,15]]},"published":{"date-parts":[[2010,5,27]]}}}