{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:42:02Z","timestamp":1761237722220},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"15","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":2298,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/uk\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Recently, several methods for analyzing phenotype data have been published, but only few are able to cope with data sets generated in different studies, with different methods, or for different species. We developed an online system in which more than 300 000 phenotypes from a wide variety of sources and screening methods can be analyzed together. Clusters of similar phenotypes are visualized as networks of highly similar phenotypes, inducing gene groups useful for functional analysis. This system is part of PhenomicDB, providing the world's largest cross-species phenotype data collection with a tool to mine its wealth of information.<\/jats:p>\n               <jats:p>Availability: Freely available at http:\/\/www.phenomicdb.de<\/jats:p>\n               <jats:p>Contact: \u00a0bertram.weiss@bayerhealthcare.com<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq311","type":"journal-article","created":{"date-parts":[[2010,6,20]],"date-time":"2010-06-20T23:54:25Z","timestamp":1277078065000},"page":"1924-1925","source":"Crossref","is-referenced-by-count":15,"title":["Phenoclustering: online mining of cross-species phenotypes"],"prefix":"10.1093","volume":"26","author":[{"given":"Philip","family":"Groth","sequence":"first","affiliation":[{"name":"1 Research Laboratories of Bayer Schering Pharma AG, 13442 Berlin, 2MetaLife AG, 79297 Winden and 3Chair for Knowledge Management in Bioinformatics, Humboldt-University of Berlin, 12489 Berlin, Germany"}]},{"given":"Ivan","family":"Kalev","sequence":"additional","affiliation":[{"name":"1 Research Laboratories of Bayer Schering Pharma AG, 13442 Berlin, 2MetaLife AG, 79297 Winden and 3Chair for Knowledge Management in Bioinformatics, Humboldt-University of Berlin, 12489 Berlin, Germany"}]},{"given":"Ivaylo","family":"Kirov","sequence":"additional","affiliation":[{"name":"1 Research Laboratories of Bayer Schering Pharma AG, 13442 Berlin, 2MetaLife AG, 79297 Winden and 3Chair for Knowledge Management in Bioinformatics, Humboldt-University of Berlin, 12489 Berlin, Germany"}]},{"given":"Borislav","family":"Traikov","sequence":"additional","affiliation":[{"name":"1 Research Laboratories of Bayer Schering Pharma AG, 13442 Berlin, 2MetaLife AG, 79297 Winden and 3Chair for Knowledge Management in Bioinformatics, Humboldt-University of Berlin, 12489 Berlin, Germany"}]},{"given":"Ulf","family":"Leser","sequence":"additional","affiliation":[{"name":"1 Research Laboratories of Bayer Schering Pharma AG, 13442 Berlin, 2MetaLife AG, 79297 Winden and 3Chair for Knowledge Management in Bioinformatics, Humboldt-University of Berlin, 12489 Berlin, Germany"}]},{"given":"Bertram","family":"Weiss","sequence":"additional","affiliation":[{"name":"1 Research Laboratories of Bayer Schering Pharma AG, 13442 Berlin, 2MetaLife AG, 79297 Winden and 3Chair for Knowledge Management in Bioinformatics, Humboldt-University of Berlin, 12489 Berlin, Germany"}]}],"member":"286","published-online":{"date-parts":[[2010,6,18]]},"reference":[{"key":"2023012508005332200_B1","doi-asserted-by":"crossref","first-page":"D696","DOI":"10.1093\/nar\/gkl662","article-title":"PhenomicDB: a new cross-species genotype\/phenotype resource","volume":"35","author":"Groth","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"2023012508005332200_B2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.2174\/157489306777828008","article-title":"Phenotype Data: a neglected resource in biomedical research?","volume":"1","author":"Groth","year":"2006","journal-title":"Curr. Bioinformatics"},{"key":"2023012508005332200_B3","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/1471-2105-9-136","article-title":"Mining phenotypes for gene function prediction","volume":"9","author":"Groth","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"2023012508005332200_B4","doi-asserted-by":"crossref","first-page":"R7","DOI":"10.1186\/gb-2004-6-1-r7","article-title":"The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information","volume":"6","author":"Smith","year":"2005","journal-title":"Genome Biol."},{"key":"2023012508005332200_B5","doi-asserted-by":"crossref","first-page":"e1000247","DOI":"10.1371\/journal.pbio.1000247","article-title":"Linking human diseases to animal models using ontology-based phenotype annotation","volume":"7","author":"Washington","year":"2009","journal-title":"PLoS Biol."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/15\/1924\/48854077\/bioinformatics_26_15_1924.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/15\/1924\/48854077\/bioinformatics_26_15_1924.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T08:01:27Z","timestamp":1674633687000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/26\/15\/1924\/189696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,18]]},"references-count":5,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2010,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btq311","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2010,8,1]]},"published":{"date-parts":[[2010,6,18]]}}}