{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T05:19:45Z","timestamp":1674710385757},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Bridges is a heuristic search tool that uses short word matches to rapidly identify local similarities between sequences. It consists of three stages: filtering input sequences, identifying local similarities and post-processing local similarities. As input sequence data are released from memory after the filtering stage, genome-scale datasets can be efficiently compared in a single run. Bridges also includes 20 parameters, which enable the user to dictate the sensitivity and specificity of a search.<\/jats:p>\n               <jats:p>Availability: Bridges is implemented in the C programming language and can be run on all platforms. Source code and documentation are available at http:\/\/github.com\/rassis\/bridges.<\/jats:p>\n               <jats:p>Contact: \u00a0kondrash@umich.edu<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq320","type":"journal-article","created":{"date-parts":[[2010,6,21]],"date-time":"2010-06-21T05:44:38Z","timestamp":1277099078000},"page":"2055-2056","source":"Crossref","is-referenced-by-count":2,"title":["Bridges: a tool for identifying local similarities in long sequences"],"prefix":"10.1093","volume":"26","author":[{"given":"Alexey S.","family":"Kondrashov","sequence":"first","affiliation":[{"name":"Center for Computational Medicine and Bioinformatics and the Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA"}]},{"given":"Raquel","family":"Assis","sequence":"additional","affiliation":[{"name":"Center for Computational Medicine and Bioinformatics and the Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA"}]}],"member":"286","published-online":{"date-parts":[[2010,6,20]]},"reference":[{"key":"2023012508030611800_B1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"2023012508030611800_B2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1126\/science.83.2148.210","article-title":"The bar \u2018gene\u2019 a duplication","volume":"83","author":"Bridges","year":"1936","journal-title":"Science"},{"key":"2023012508030611800_B3","first-page":"656","article-title":"BLAT\u2014The BLAST-like alignment tool","volume":"12","author":"Kent","year":"2002","journal-title":"Genome Res."},{"key":"2023012508030611800_B4","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1073\/pnas.85.8.2444","article-title":"Improved tools for biological sequence comparison","volume":"85","author":"Pearson","year":"1988","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2023012508030611800_B5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0022-2836(81)90087-5","article-title":"Identification of common molecular subsequences","volume":"147","author":"Smith","year":"1981","journal-title":"J. Mol. Biol."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/16\/2055\/48853456\/bioinformatics_26_16_2055.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/16\/2055\/48853456\/bioinformatics_26_16_2055.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T08:03:55Z","timestamp":1674633835000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/26\/16\/2055\/216417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,20]]},"references-count":5,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2010,8,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btq320","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2010,8,15]]},"published":{"date-parts":[[2010,6,20]]}}}