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CplexA is a Mathematica package that uses functional programming to efficiently compute probabilities and average properties over such exponentially large number of states from the energetics of the interactions. The package is particularly suited to study gene expression at complex promoters controlled by multiple, local and distal, DNA binding sites for transcription factors.<\/jats:p>\n               <jats:p>Availability: CplexA is freely available together with documentation at http:\/\/sourceforge.net\/projects\/cplexa\/<\/jats:p>\n               <jats:p>Contact: \u00a0j.vilar@ikerbasque.org; lsaiz@ucdavis.edu<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq328","type":"journal-article","created":{"date-parts":[[2010,6,20]],"date-time":"2010-06-20T23:54:25Z","timestamp":1277078065000},"page":"2060-2061","source":"Crossref","is-referenced-by-count":37,"title":["CplexA: a <i>Mathematica<\/i> package to study macromolecular-assembly control of gene expression"],"prefix":"10.1093","volume":"26","author":[{"given":"Jose M.G.","family":"Vilar","sequence":"first","affiliation":[{"name":"1 Biophysics Unit (CSIC-UPV\/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country, PO Box 644, 48080 Bilbao, 2IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain and 3Department of Biomedical Engineering, University of California, 451 E. Health Sciences Drive, Davis, CA 95616, USA"},{"name":"1 Biophysics Unit (CSIC-UPV\/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country, PO Box 644, 48080 Bilbao, 2IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain and 3Department of Biomedical Engineering, University of California, 451 E. Health Sciences Drive, Davis, CA 95616, USA"}]},{"given":"Leonor","family":"Saiz","sequence":"additional","affiliation":[{"name":"1 Biophysics Unit (CSIC-UPV\/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country, PO Box 644, 48080 Bilbao, 2IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain and 3Department of Biomedical Engineering, University of California, 451 E. 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