{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:22:39Z","timestamp":1772151759879,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Chromaligner is a tool for chromatogram alignment to align retention time for chromatographic methods coupled to spectrophotometers such as high performance liquid chromatography and capillary electrophoresis for metabolomics works. Chromaligner resolves peak shifts by a constrained chromatogram alignment. For a collection of chromatograms and a set of defined peaks, Chromaligner aligns the chromatograms on defined peaks using correlation warping (COW). Chromaligner is faster than the original COW algorithm by k2 times, where k is the number of defined peaks in a chromatogram. It also provides alignments based on known component peaks to reach the best results for further chemometric analysis.<\/jats:p>\n               <jats:p>Availability: Chromaligner is freely accessible at http:\/\/cmdd.csie.ntu.edu.tw\/\u223cchromaligner<\/jats:p>\n               <jats:p>Contact: \u00a0kuoch@ntu.edu.tw; yjtseng@csie.ntu.edu.tw<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq337","type":"journal-article","created":{"date-parts":[[2010,6,25]],"date-time":"2010-06-25T00:19:35Z","timestamp":1277425175000},"page":"2338-2339","source":"Crossref","is-referenced-by-count":17,"title":["Chromaligner: a web server for chromatogram alignment"],"prefix":"10.1093","volume":"26","author":[{"given":"San-Yuan","family":"Wang","sequence":"first","affiliation":[{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"},{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsung-Jung","family":"Ho","sequence":"additional","affiliation":[{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"},{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Hua","family":"Kuo","sequence":"additional","affiliation":[{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"},{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufeng J.","family":"Tseng","sequence":"additional","affiliation":[{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"},{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"},{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"},{"name":"1 Department of Computer Science and Information Engineering, 2The Metabolomics Group, 3School of Pharmacy, College of Medicine and 4Graduate Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,6,23]]},"reference":[{"key":"2023012508241681800_B1","doi-asserted-by":"crossref","first-page":"7012","DOI":"10.1021\/ac800920h","article-title":"Optimized time alignment algorithm for LC-MS data: correlation optimized warping using component detection algorithm-selected mass chromatograms","volume":"80","author":"Christin","year":"2008","journal-title":"Anal. 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