{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T18:52:40Z","timestamp":1676746360216},"reference-count":2,"publisher":"Oxford University Press (OUP)","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Protein microarrays are well-established as sensitive tools for proteomics. Particularly, the microspot immunoassay (MIA) platform enables a quantitative analysis of (phospho-) proteins in complex solutions (e.g. cell lysates or blood plasma) and with low consumption of samples and reagents. Despite numerous biological and clinical applications of MIAs there is currently no user-friendly open source data analysis software available with versatile options for data analysis and data visualization. Here, we introduce the open source software QuantProReloaded that is specifically designed for the analysis of data from MIA experiments.<\/jats:p>\n               <jats:p>Availability and implementation: QuantProReloaded is written in R and Java and is open for download under the BSB license at http:\/\/code.google.com\/p\/quantproreloaded\/<\/jats:p>\n               <jats:p>Contact: \u00a0a.joecker@dkfz.de<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq443","type":"journal-article","created":{"date-parts":[[2010,8,14]],"date-time":"2010-08-14T00:13:54Z","timestamp":1281744834000},"page":"2480-2481","source":"Crossref","is-referenced-by-count":3,"title":["QuantProReloaded: quantitative analysis of microspot immunoassays"],"prefix":"10.1093","volume":"26","author":[{"given":"Anika","family":"J\u00f6cker","sequence":"first","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Sonntag","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frauke","family":"Henjes","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"G\u00f6tschel","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achim","family":"Tresch","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Bei\u00dfbarth","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Wiemann","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Korf","sequence":"additional","affiliation":[{"name":"1 Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, 2Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, Munich and 3Department of Medical Statistics, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,8,12]]},"reference":[{"key":"2023012508171718800_B1","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.1002\/pmic.200800112","article-title":"Quantitative protein microarrays for time-resolved measurements of protein phosphorylation","volume":"8","author":"Korf","year":"2008","journal-title":"Proteomics"},{"key":"2023012508171718800_B2","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1093\/bioinformatics\/btl093","article-title":"ProMAT: protein microarray analysis tool","volume":"22","author":"White","year":"2006","journal-title":"Bioinformatics"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/19\/2480\/48857043\/bioinformatics_26_19_2480.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/19\/2480\/48857043\/bioinformatics_26_19_2480.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T08:18:47Z","timestamp":1674634727000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/26\/19\/2480\/229199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,12]]},"references-count":2,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2010,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btq443","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2010,10,1]]},"published":{"date-parts":[[2010,8,12]]}}}