{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:49:24Z","timestamp":1774525764789,"version":"3.50.1"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"22","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":2189,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/uk\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The GeneMANIA Cytoscape plugin brings fast gene function prediction capabilities to the desktop. GeneMANIA identifies the most related genes to a query gene set using a guilt-by-association approach. The plugin uses over 800 networks from six organisms and each related gene is traceable to the source network used to make the prediction. Users may add their own interaction networks and expression profile data to complement or override the default data.<\/jats:p>\n               <jats:p>Availability and Implementation: The GeneMANIA Cytoscape plugin is implemented in Java and is freely available at http:\/\/www.genemania.org\/plugin\/.<\/jats:p>\n               <jats:p>Contact: \u00a0gary.bader@utoronto.ca; quaid.morris@utoronto.ca<\/jats:p>","DOI":"10.1093\/bioinformatics\/btq562","type":"journal-article","created":{"date-parts":[[2010,10,19]],"date-time":"2010-10-19T04:15:50Z","timestamp":1287461750000},"page":"2927-2928","source":"Crossref","is-referenced-by-count":560,"title":["GeneMANIA Cytoscape plugin: fast gene function predictions on the desktop"],"prefix":"10.1093","volume":"26","author":[{"given":"J.","family":"Montojo","sequence":"first","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"K.","family":"Zuberi","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"H.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"F.","family":"Kazi","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"G.","family":"Wright","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"S. L.","family":"Donaldson","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"Q.","family":"Morris","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]},{"given":"G. D.","family":"Bader","sequence":"additional","affiliation":[{"name":"Banting and Best Department of Medical Research and Departments of Molecular Genetics and Computer Science, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada"}]}],"member":"286","published-online":{"date-parts":[[2010,10,5]]},"reference":[{"key":"2023012507561280300_B1","doi-asserted-by":"crossref","first-page":"D885","DOI":"10.1093\/nar\/gkn764","article-title":"NCBI GEO: archive for high-throughput functional genomic data","volume":"37","author":"Barrett","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"2023012507561280300_B2","doi-asserted-by":"crossref","first-page":"D637","DOI":"10.1093\/nar\/gkm1001","article-title":"The BioGRID Interaction Database: 2008 update","volume":"36","author":"Breitkreutz","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"2023012507561280300_B3","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1093\/bioinformatics\/bti273","article-title":"Online predicted human interaction database","volume":"21","author":"Brown","year":"2005","journal-title":"Bioinformatics"},{"key":"2023012507561280300_B4","doi-asserted-by":"crossref","first-page":"e1000046","DOI":"10.1371\/journal.pmed.1000046","article-title":"A compendium of potential biomarkers of pancreatic cancer","volume":"6","author":"Harsha","year":"2009","journal-title":"PLoS Med"},{"key":"2023012507561280300_B5","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/bioinformatics\/btq262","article-title":"Fast integration of heterogeneous data sources for predicting gene function with limited annotation","volume":"26","author":"Mostafavi","year":"2010","journal-title":"Bioinformatics"},{"key":"2023012507561280300_B6","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/gb-2008-9-s1-s4","article-title":"GeneMANIA: a real-time multiple association network integration algorithm for prediction gene function","volume":"9","author":"Mostafavi","year":"2008","journal-title":"Genome Biol."},{"key":"2023012507561280300_B7","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/gb-2008-9-s1-s2","article-title":"A critical assessment of Mus musculus gene function prediction using integrated genomic evidence","volume":"9","author":"Pena-Castillo","year":"2008","journal-title":"Genome Biol."},{"key":"2023012507561280300_B8","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"key":"2023012507561280300_B9","doi-asserted-by":"crossref","first-page":"W214","DOI":"10.1093\/nar\/gkq537","article-title":"The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function","volume":"38","author":"Warde-Farley","year":"2010","journal-title":"Nucleic Acids Res."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/22\/2927\/48852457\/bioinformatics_26_22_2927.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/26\/22\/2927\/48852457\/bioinformatics_26_22_2927.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T07:56:36Z","timestamp":1674633396000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/26\/22\/2927\/228740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,5]]},"references-count":9,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2010,11,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btq562","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2010,11,15]]},"published":{"date-parts":[[2010,10,5]]}}}