{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T02:28:18Z","timestamp":1784082498502,"version":"3.55.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: Genetic studies focus on increasingly larger genomic regions of both extant and ancient DNA, and there is a need for simulation software to match these technological advances. We present here a new coalescent-based simulation program fastsimcoal, which is able to quickly simulate a variety of genetic markers scattered over very long genomic regions with arbitrary recombination patterns under complex evolutionary scenarios.<\/jats:p>\n               <jats:p>Availability and Implementation: fastsimcoal is a C++ program compiled for Windows, MacOsX and Linux platforms. It is freely available at cmpg.unibe.ch\/software\/fastsimcoal\/, together with its detailed user manual and example input files.<\/jats:p>\n               <jats:p>Contact: \u00a0laurent.excoffier@iee.unibe.ch<\/jats:p>\n               <jats:p>Supplementary Information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btr124","type":"journal-article","created":{"date-parts":[[2011,3,13]],"date-time":"2011-03-13T23:38:49Z","timestamp":1300059529000},"page":"1332-1334","source":"Crossref","is-referenced-by-count":435,"title":["fastsimcoal: a continuous-time coalescent simulator of genomic diversity under arbitrarily complex evolutionary scenarios"],"prefix":"10.1093","volume":"27","author":[{"given":"Laurent","family":"Excoffier","sequence":"first","affiliation":[{"name":"1 Institute of Ecology and Evolution, University of Berne, 3012 Berne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Institute of Ecology and Evolution, University of Berne, 3012 Berne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Foll","sequence":"additional","affiliation":[{"name":"1 Institute of Ecology and Evolution, University of Berne, 3012 Berne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Institute of Ecology and Evolution, University of Berne, 3012 Berne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,3,12]]},"reference":[{"key":"2023012512190948300_B1","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1093\/bioinformatics\/bti154","article-title":"Serial SimCoal: a population genetics model for data from multiple populations and points in time","volume":"21","author":"Anderson","year":"2005","journal-title":"Bioinformatics"},{"key":"2023012512190948300_B2","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1093\/genetics\/162.4.2025","article-title":"Approximate Bayesian computation in population genetics","volume":"162","author":"Beaumont","year":"2002","journal-title":"Genetics"},{"key":"2023012512190948300_B3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2174\/138920208784340759","article-title":"Simulation of genomes: a review","volume":"9","author":"Carvajal-Rodriguez","year":"2008","journal-title":"Curr. 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