{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:23:42Z","timestamp":1772151822560,"version":"3.50.1"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: AStream, an R-statistical software package for the curation and identification of feature peaks extracted from liquid chromatography mass spectrometry (LC\/MS) metabolomics data, is described. AStream detects isotopic, fragment and adduct patterns by identifying feature pairs that fulfill expected relational patterns. Data reduction by AStream allows compounds to be identified reliably and subsequently linked to metabolite databases. AStream provides researchers with a fast, reliable tool for summarizing metabolomic data, notably reducing curation time and increasing consistency of results.<\/jats:p>\n               <jats:p>Availability: The AStream R package and a study example can be freely accessed at http:\/\/www.urr.cat\/AStream\/AStream.html.<\/jats:p>\n               <jats:p>Contact: \u00a0smarsal@ir.vhebron.net; ajulia@ir.vhebron.net<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btr138","type":"journal-article","created":{"date-parts":[[2011,3,18]],"date-time":"2011-03-18T01:09:30Z","timestamp":1300410570000},"page":"1339-1340","source":"Crossref","is-referenced-by-count":46,"title":["AStream: an R package for annotating LC\/MS metabolomic data"],"prefix":"10.1093","volume":"27","author":[{"given":"Arnald","family":"Alonso","sequence":"first","affiliation":[{"name":"1 Grup de Recerca de Reumatologia, Institut de Recerca de l'Hospital Universitari Vall d'Hebr\u00f3n (Univ. Aut\u00f2noma de Barcelona), Barcelona, 2Metabolomics Platform, URV\u2212IISPV, Tarragona, 3CIBERDEM (CIBER de Diabetes y Enfermedades Metab\u00f3licas Asociadas), 4Endocrinology Unit, Hospital Sant Joan de D\u00e9u (UB), Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Juli\u00e0","sequence":"additional","affiliation":[{"name":"1 Grup de Recerca de Reumatologia, Institut de Recerca de l'Hospital Universitari Vall d'Hebr\u00f3n (Univ. Aut\u00f2noma de Barcelona), Barcelona, 2Metabolomics Platform, URV\u2212IISPV, Tarragona, 3CIBERDEM (CIBER de Diabetes y Enfermedades Metab\u00f3licas Asociadas), 4Endocrinology Unit, Hospital Sant Joan de D\u00e9u (UB), Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoni","family":"Beltran","sequence":"additional","affiliation":[{"name":"1 Grup de Recerca de Reumatologia, Institut de Recerca de l'Hospital Universitari Vall d'Hebr\u00f3n (Univ. 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