{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T18:32:29Z","timestamp":1764873149292},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: Infectious disease research is generating an increasing amount of disparate data on pathogenic systems. There is a growing need for resources that effectively integrate, analyze, deliver and visualize these data, both to improve our understanding of infectious diseases and to facilitate the development of strategies for disease control and prevention.<\/jats:p>\n               <jats:p>Results: We have developed Disease View, an online host\u2013pathogen resource that enables infectious disease-centric access, analysis and visualization of host\u2013pathogen interactions. In this resource, we associate infectious diseases with corresponding pathogens, provide information on pathogens, pathogen virulence genes and the genetic and chemical evidences for the human genes that are associated with the diseases. We also deliver the relationships between pathogens, genes and diseases in an interactive graph and provide the geolocation reports of associated diseases around the globe in real time. Unlike many other resources, we have applied an iterative, user-centered design process to the entire resource development, including data acquisition, analysis and visualization.<\/jats:p>\n               <jats:p>Availability and Implementation: Freely available at http:\/\/www.patricbrc.org; all major web browsers supported.<\/jats:p>\n               <jats:p>Contact: \u00a0cmao@vbi.vt.edu<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btr391","type":"journal-article","created":{"date-parts":[[2011,6,29]],"date-time":"2011-06-29T00:15:25Z","timestamp":1309306525000},"page":"2279-2287","source":"Crossref","is-referenced-by-count":18,"title":["Integration and visualization of host\u2013pathogen data related to infectious diseases"],"prefix":"10.1093","volume":"27","author":[{"given":"Timothy","family":"Driscoll","sequence":"first","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph L.","family":"Gabbard","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunhong","family":"Mao","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oral","family":"Dalay","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maulik","family":"Shukla","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clark C.","family":"Freifeld","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Gatewood","family":"Hoen","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S.","family":"Brownstein","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno W.","family":"Sobral","sequence":"additional","affiliation":[{"name":"1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061 and 2Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,6,27]]},"reference":[{"key":"2023012511514400000_B1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. 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