{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:22:49Z","timestamp":1791217369604,"version":"4.1.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The advent of high-throughput sequencers (HTS) introduced the need of new tools in order to analyse the large amount of data that those machines are able to produce. The mandatory first step for a wide range of analyses is the alignment of the sequences against a reference genome. We present a major update to our rNA (randomized Numerical Aligner) tool. The main feature of rNA is the fact that it achieves an accuracy greater than the majority of other tools in a feasible amount of time. rNA executables and source codes are freely downloadable at http:\/\/iga-rna.sourceforge.net\/.<\/jats:p>\n               <jats:p>Contact: \u00a0vezzi@appliedgenomics.org; delfabbro@appliedgenomics.org<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btr617","type":"journal-article","created":{"date-parts":[[2011,11,15]],"date-time":"2011-11-15T15:18:21Z","timestamp":1321370301000},"page":"123-124","source":"Crossref","is-referenced-by-count":39,"title":["rNA: a fast and accurate short reads numerical aligner"],"prefix":"10.1093","volume":"28","author":[{"given":"Francesco","family":"Vezzi","sequence":"first","affiliation":[{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"},{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Del Fabbro","sequence":"additional","affiliation":[{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"},{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"},{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandru I.","family":"Tomescu","sequence":"additional","affiliation":[{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"},{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Policriti","sequence":"additional","affiliation":[{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"},{"name":"1 Department of Mathematics and Computer Science, University of Udine, Udine, 2Istituto di Genomica Applicata, Udine, 3Department of Agriculture and Environmental Sciences, University of Udine, Udine, Italy and 4Faculty of Mathematics and Computer Science, University of Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,11,13]]},"reference":[{"key":"2023061011442194200_B1","doi-asserted-by":"crossref","first-page":"e7767","DOI":"10.1371\/journal.pone.0007767","article-title":"BFAST: an alignment tool for large scale genome resequencing","volume":"4","author":"Homer","year":"2009","journal-title":"PloS one"},{"key":"2023061011442194200_B2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1147\/rd.312.0249","article-title":"Efficient randomized pattern-matching algorithms","volume":"31","author":"Karp","year":"1987","journal-title":"IBM J. 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