{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:55:04Z","timestamp":1793332504138,"version":"4.5.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":1746,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Motivation: High-throughput sequencing (HTS) technologies have made low-cost sequencing of large numbers of samples commonplace. An explosion in the type, not just number, of sequencing experiments has also taken place including genome re-sequencing, population-scale variation detection, whole transcriptome sequencing and genome-wide analysis of protein-bound nucleic acids.<\/jats:p>\n                  <jats:p>Results: We present Artemis as a tool for integrated visualization and computational analysis of different types of HTS datasets in the context of a reference genome and its corresponding annotation.<\/jats:p>\n                  <jats:p>Availability: Artemis is freely available (under a GPL licence) for download (for MacOSX, UNIX and Windows) at the Wellcome Trust Sanger Institute websites: http:\/\/www.sanger.ac.uk\/resources\/software\/artemis\/.<\/jats:p>\n                  <jats:p>Contact: \u00a0artemis@sanger.ac.uk; tjc@sanger.ac.uk<\/jats:p>","DOI":"10.1093\/bioinformatics\/btr703","type":"journal-article","created":{"date-parts":[[2011,12,23]],"date-time":"2011-12-23T21:37:52Z","timestamp":1324676272000},"page":"464-469","source":"Crossref","is-referenced-by-count":1203,"title":["Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data"],"prefix":"10.1093","volume":"28","author":[{"given":"Tim","family":"Carver","sequence":"first","affiliation":[{"name":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon R.","family":"Harris","sequence":"additional","affiliation":[{"name":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Berriman","sequence":"additional","affiliation":[{"name":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Parkhill","sequence":"additional","affiliation":[{"name":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline A.","family":"McQuillan","sequence":"additional","affiliation":[{"name":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,12,22]]},"reference":[{"key":"2023012512182089200_B1","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/nature09534","article-title":"A map of human genome variation from population-scale sequencing","volume":"467","author":"Altshuler","year":"2010","journal-title":"Nature"},{"key":"2023012512182089200_B2","doi-asserted-by":"crossref","first-page":"R106","DOI":"10.1186\/gb-2010-11-10-r106","article-title":"Differential expression analysis for sequence count data","volume":"11","author":"Anders","year":"2010","journal-title":"Genome Biol."},{"key":"2023012512182089200_B3","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/nature08160","article-title":"The genome of the blood fluke Schistosoma mansoni","volume":"460","author":"Berriman","year":"2009","journal-title":"Nature"},{"key":"2023012512182089200_B4","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1101\/gr.109553.110","article-title":"Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq","volume":"20","author":"Bruno","year":"2010","journal-title":"Genome Res."},{"key":"2023012512182089200_B5","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1093\/bioinformatics\/bti553","article-title":"ACT: the Artemis comparison tool","volume":"21","author":"Carver","year":"2005","journal-title":"Bioinformatics"},{"key":"2023012512182089200_B6","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/bioinformatics\/btq010","article-title":"BamView: viewing mapped read alignment data in the context of the reference sequence","volume":"26","author":"Carver","year":"2010","journal-title":"Bioinformatics"},{"key":"2023012512182089200_B7","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.mib.2010.09.009","article-title":"Studying bacterial transcriptomes using RNA-seq","volume":"13","author":"Croucher","year":"2010","journal-title":"Curr. 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