{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:43:23Z","timestamp":1769733803882,"version":"3.49.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":1710,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Motivation: Most anatomical ontologies are species-specific, whereas a framework for comparative studies is needed. We describe the vertebrate Homologous Organs Groups ontology, vHOG, used to compare expression patterns between species.<\/jats:p><jats:p>Results: vHOG is a multispecies anatomical ontology for the vertebrate lineage. It is based on the HOGs used in the Bgee database of gene expression evolution. vHOG version 1.4 includes 1184 terms, follows OBO principles and is based on the Common Anatomy Reference Ontology (CARO). vHOG only describes structures with historical homology relations between model vertebrate species. The mapping to species-specific anatomical ontologies is provided as a separate file, so that no homology hypothesis is stated within the ontology itself. Each mapping has been manually reviewed, and we provide support codes and references when available.<\/jats:p><jats:p>Availability and implementation: vHOG is available from the Bgee download site (http:\/\/bgee.unil.ch\/), as well as from the OBO Foundry and the NCBO Bioportal websites.<\/jats:p><jats:p>Contact: \u00a0bgee@isb-sib.ch; frederic.bastian@unil.ch<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts048","type":"journal-article","created":{"date-parts":[[2012,1,28]],"date-time":"2012-01-28T05:35:03Z","timestamp":1327728903000},"page":"1017-1020","source":"Crossref","is-referenced-by-count":19,"title":["vHOG, a multispecies vertebrate ontology of homologous organs groups"],"prefix":"10.1093","volume":"28","author":[{"given":"Anne","family":"Niknejad","sequence":"first","affiliation":[{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}]},{"given":"Aur\u00e9lie","family":"Comte","sequence":"additional","affiliation":[{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}]},{"given":"Gilles","family":"Parmentier","sequence":"additional","affiliation":[{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}]},{"given":"Julien","family":"Roux","sequence":"additional","affiliation":[{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}]},{"given":"Frederic B.","family":"Bastian","sequence":"additional","affiliation":[{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}]},{"given":"Marc","family":"Robinson-Rechavi","sequence":"additional","affiliation":[{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"},{"name":"1 Department of Ecology and Evolution, Biophore, University of Lausanne and 2Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}]}],"member":"286","published-online":{"date-parts":[[2012,1,27]]},"reference":[{"key":"2023012512205522600_B1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-84628-885-2_1","article-title":"Anatomical ontologies for model organisms: the fungi and animals","volume-title":"Anatomy Ontologies for Bioinformatics: Principles and Practice.","author":"Bard","year":"2008"},{"key":"2023012512205522600_B2","doi-asserted-by":"crossref","first-page":"D396","DOI":"10.1093\/nar\/gkn803","article-title":"The GOA database in 2009, \u00c4\u00eean integrated Gene Ontology annotation resource","volume":"37","author":"Barrell","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"2023012512205522600_B3","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/978-3-540-69828-9_12","article-title":"Bgee: integrating and comparing heterogeneous transcriptome data among species","volume-title":"Data Integration in the Life Sciences.","author":"Bastian","year":"2008"},{"key":"2023012512205522600_B4","first-page":"77","article-title":"[Hoxa5: a master gene with multifaceted roles]","volume":"25","author":"Boucherat","year":"2009","journal-title":"Med. 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